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PIK3R1 negatively regulates the epithelial-mesenchymal transition and stem-like phenotype of renal cancer cells through the AKT/GSK3β/CTNNB1 signaling pathway.
Lin Y, Yang Z, Xu A, Dong P, Huang Y, Liu H, Li F, Wang H, Xu Q, Wang Y, Sun D, Zou Y, Zou X, Wang Y, Zhang D, Liu H, Wu X, Zhang M, Fu Y, Cai Z, Liu C, Wu S. Lin Y, et al. Among authors: huang y. Sci Rep. 2015 Mar 11;5:8997. doi: 10.1038/srep08997. Sci Rep. 2015. PMID: 25757764 Free PMC article.
The Wilms tumor gene, Wt1, is critical for mouse spermatogenesis via regulation of sertoli cell polarity and is associated with non-obstructive azoospermia in humans.
Wang XN, Li ZS, Ren Y, Jiang T, Wang YQ, Chen M, Zhang J, Hao JX, Wang YB, Sha RN, Huang Y, Liu X, Hu JC, Sun GQ, Li HG, Xiong CL, Xie J, Jiang ZM, Cai ZM, Wang J, Wang J, Huff V, Gui YT, Gao F. Wang XN, et al. Among authors: huang y. PLoS Genet. 2013;9(8):e1003645. doi: 10.1371/journal.pgen.1003645. Epub 2013 Aug 1. PLoS Genet. 2013. PMID: 23935527 Free PMC article.
Effect of Apatinib Plus Pegylated Liposomal Doxorubicin vs Pegylated Liposomal Doxorubicin Alone on Platinum-Resistant Recurrent Ovarian Cancer: The APPROVE Randomized Clinical Trial.
Wang T, Tang J, Yang H, Yin R, Zhang J, Zhou Q, Liu Z, Cao L, Li L, Huang Y, Jiang K, Wang W, She F, Guan N, Hou Z, Li N, Wu L. Wang T, et al. Among authors: huang y. JAMA Oncol. 2022 Aug 1;8(8):1169-1176. doi: 10.1001/jamaoncol.2022.2253. JAMA Oncol. 2022. PMID: 35771546 Free PMC article. Clinical Trial.
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