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Leinamycin E1 acting as an anticancer prodrug activated by reactive oxygen species.
Huang SX, Yun BS, Ma M, Basu HS, Church DR, Ingenhorst G, Huang Y, Yang D, Lohman JR, Tang GL, Ju J, Liu T, Wilding G, Shen B. Huang SX, et al. Among authors: huang y. Proc Natl Acad Sci U S A. 2015 Jul 7;112(27):8278-83. doi: 10.1073/pnas.1506761112. Epub 2015 Jun 8. Proc Natl Acad Sci U S A. 2015. PMID: 26056295 Free PMC article.
Germicidins H-J from Streptomyces sp. CB00361.
Ma M, Rateb ME, Yang D, Rudolf JD, Zhu X, Huang Y, Zhao LX, Jiang Y, Duan Y, Shen B. Ma M, et al. Among authors: huang y. J Antibiot (Tokyo). 2017 Feb;70(2):200-203. doi: 10.1038/ja.2016.100. Epub 2016 Aug 10. J Antibiot (Tokyo). 2017. PMID: 27507632 No abstract available.
Strain Prioritization and Genome Mining for Enediyne Natural Products.
Yan X, Ge H, Huang T, Hindra, Yang D, Teng Q, Crnovčić I, Li X, Rudolf JD, Lohman JR, Gansemans Y, Zhu X, Huang Y, Zhao LX, Jiang Y, Van Nieuwerburgh F, Rader C, Duan Y, Shen B. Yan X, et al. Among authors: huang t, huang y. mBio. 2016 Dec 20;7(6):e02104-16. doi: 10.1128/mBio.02104-16. mBio. 2016. PMID: 27999165 Free PMC article.
Discovery of the leinamycin family of natural products by mining actinobacterial genomes.
Pan G, Xu Z, Guo Z, Hindra, Ma M, Yang D, Zhou H, Gansemans Y, Zhu X, Huang Y, Zhao LX, Jiang Y, Cheng J, Van Nieuwerburgh F, Suh JW, Duan Y, Shen B. Pan G, et al. Among authors: huang y. Proc Natl Acad Sci U S A. 2017 Dec 26;114(52):E11131-E11140. doi: 10.1073/pnas.1716245115. Epub 2017 Dec 11. Proc Natl Acad Sci U S A. 2017. PMID: 29229819 Free PMC article.
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