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A Comprehensive Map of CNS Transduction by Eight Recombinant Adeno-associated Virus Serotypes Upon Cerebrospinal Fluid Administration in Pigs.
Sorrentino NC, Maffia V, Strollo S, Cacace V, Romagnoli N, Manfredi A, Ventrella D, Dondi F, Barone F, Giunti M, Graham AR, Huang Y, Kalled SL, Auricchio A, Bacci ML, Surace EM, Fraldi A. Sorrentino NC, et al. Among authors: huang y. Mol Ther. 2016 Feb;24(2):276-286. doi: 10.1038/mt.2015.212. Epub 2015 Dec 7. Mol Ther. 2016. PMID: 26639405 Free PMC article.
Myostatin and activin blockade by engineered follistatin results in hypertrophy and improves dystrophic pathology in mdx mouse more than myostatin blockade alone.
Iskenderian A, Liu N, Deng Q, Huang Y, Shen C, Palmieri K, Crooker R, Lundberg D, Kastrapeli N, Pescatore B, Romashko A, Dumas J, Comeau R, Norton A, Pan J, Rong H, Derakhchan K, Ehmann DE. Iskenderian A, et al. Among authors: huang y. Skelet Muscle. 2018 Oct 27;8(1):34. doi: 10.1186/s13395-018-0180-z. Skelet Muscle. 2018. PMID: 30368252 Free PMC article.
VEGFR-1/Flt-1 inhibition increases angiogenesis and improves muscle function in a mouse model of Duchenne muscular dystrophy.
Bosco J, Zhou Z, Gabriëls S, Verma M, Liu N, Miller BK, Gu S, Lundberg DM, Huang Y, Brown E, Josiah S, Meiyappan M, Traylor MJ, Chen N, Asakura A, De Jonge N, Blanchetot C, de Haard H, Duffy HS, Keefe D. Bosco J, et al. Among authors: huang y. Mol Ther Methods Clin Dev. 2021 Mar 23;21:369-381. doi: 10.1016/j.omtm.2021.03.013. eCollection 2021 Jun 11. Mol Ther Methods Clin Dev. 2021. PMID: 33898634 Free PMC article.
Gene therapy for cross-correction of somatic organs and the CNS in mucopolysaccharidosis II in rodents and non-human primates.
Chen N, Ehmann DE, Crooker R, Derakhchan K, Fang X, Felice B, Galbreath EJ, Glaus C, Gu H, Huang Y, Li C, Li X, Liu N, Palmieri K, Simic D, Sypek J, Thompson S, Winkelmann CT, Choi VW. Chen N, et al. Among authors: huang y. Mol Ther Methods Clin Dev. 2023 Mar 28;29:286-302. doi: 10.1016/j.omtm.2023.03.014. eCollection 2023 Jun 8. Mol Ther Methods Clin Dev. 2023. PMID: 37359415 Free PMC article.
Enhancing the Therapeutic Potential of Sulfamidase for the Treatment of Mucopolysaccharidosis IIIA.
Sorrentino NC, Cacace V, De Risi M, Maffia V, Strollo S, Tedesco N, Nusco E, Romagnoli N, Ventrella D, Huang Y, Liu N, Kalled SL, Choi VW, De Leonibus E, Fraldi A. Sorrentino NC, et al. Among authors: huang y. Mol Ther Methods Clin Dev. 2019 Oct 28;15:333-342. doi: 10.1016/j.omtm.2019.10.009. eCollection 2019 Dec 13. Mol Ther Methods Clin Dev. 2019. PMID: 31788497 Free PMC article.
Intravenously Administered Recombinant Human Type VII Collagen Derived from Chinese Hamster Ovary Cells Reverses the Disease Phenotype in Recessive Dystrophic Epidermolysis Bullosa Mice.
Hou Y, Guey LT, Wu T, Gao R, Cogan J, Wang X, Hong E, Vivian Ning W, Keene D, Liu N, Huang Y, Kaftan C, Tangarone B, Quinones-Garcia I, Uitto J, Francone OL, Woodley DT, Chen M. Hou Y, et al. Among authors: huang y. J Invest Dermatol. 2015 Dec;135(12):3060-3067. doi: 10.1038/jid.2015.291. Epub 2015 Jul 23. J Invest Dermatol. 2015. PMID: 26203639 Free article.
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