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Anchor-based classification and type-C inhibitors for tyrosine kinases.
Hsu KC, Sung TY, Lin CT, Chiu YY, Hsu JT, Hung HC, Sun CM, Barve I, Chen WL, Huang WC, Huang CT, Chen CH, Yang JM. Hsu KC, et al. Among authors: huang ct, huang wc. Sci Rep. 2015 Jun 16;5:10938. doi: 10.1038/srep10938. Sci Rep. 2015. PMID: 26077136 Free PMC article.
Blocking c-Met-mediated PARP1 phosphorylation enhances anti-tumor effects of PARP inhibitors.
Du Y, Yamaguchi H, Wei Y, Hsu JL, Wang HL, Hsu YH, Lin WC, Yu WH, Leonard PG, Lee GR 4th, Chen MK, Nakai K, Hsu MC, Chen CT, Sun Y, Wu Y, Chang WC, Huang WC, Liu CL, Chang YC, Chen CH, Park M, Jones P, Hortobagyi GN, Hung MC. Du Y, et al. Among authors: huang wc. Nat Med. 2016 Feb;22(2):194-201. doi: 10.1038/nm.4032. Epub 2016 Jan 18. Nat Med. 2016. PMID: 26779812 Free PMC article.
Definition of PKC-α, CDK6, and MET as therapeutic targets in triple-negative breast cancer.
Hsu YH, Yao J, Chan LC, Wu TJ, Hsu JL, Fang YF, Wei Y, Wu Y, Huang WC, Liu CL, Chang YC, Wang MY, Li CW, Shen J, Chen MK, Sahin AA, Sood A, Mills GB, Yu D, Hortobagyi GN, Hung MC. Hsu YH, et al. Among authors: huang wc. Cancer Res. 2014 Sep 1;74(17):4822-35. doi: 10.1158/0008-5472.CAN-14-0584. Epub 2014 Jun 26. Cancer Res. 2014. PMID: 24970481 Free PMC article.
4-Acetylantroquinonol B suppresses autophagic flux and improves cisplatin sensitivity in highly aggressive epithelial cancer through the PI3K/Akt/mTOR/p70S6K signaling pathway.
Liu M, Bamodu OA, Huang WC, Zucha MA, Lin YK, Wu ATH, Huang CC, Lee WH, Yuan CC, Hsiao M, Deng L, Tzeng YM, Yeh CT. Liu M, et al. Among authors: huang cc, huang wc. Toxicol Appl Pharmacol. 2017 Jun 15;325:48-60. doi: 10.1016/j.taap.2017.04.003. Epub 2017 Apr 10. Toxicol Appl Pharmacol. 2017. PMID: 28408137
4-Acetylantroquinonol B induced DNA damage response signaling and apoptosis via suppressing CDK2/CDK4 expression in triple negative breast cancer cells.
Satriyo PB, Su CM, Ong JR, Huang WC, Fong IH, Lin CC, Aryandono T, Haryana SM, Deng L, Huang CC, Tzeng YM, Chao TY, Liu HW, Yeh CT. Satriyo PB, et al. Among authors: huang cc, huang wc. Toxicol Appl Pharmacol. 2021 Jul 1;422:115493. doi: 10.1016/j.taap.2021.115493. Epub 2021 Mar 13. Toxicol Appl Pharmacol. 2021. PMID: 33727089
2,109 results