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Tumor-induced reshuffling of lipid composition on the endoplasmic reticulum membrane sustains macrophage survival and pro-tumorigenic activity.
Di Conza G, Tsai CH, Gallart-Ayala H, Yu YR, Franco F, Zaffalon L, Xie X, Li X, Xiao Z, Raines LN, Falquet M, Jalil A, Locasale JW, Percipalle P, Masson D, Huang SC, Martinon F, Ivanisevic J, Ho PC. Di Conza G, et al. Among authors: huang sc. Nat Immunol. 2021 Nov;22(11):1403-1415. doi: 10.1038/s41590-021-01047-4. Epub 2021 Oct 22. Nat Immunol. 2021. PMID: 34686867 Free PMC article.
Is glucose the scapegoat for tumor evasion?
Raines LN, Huang SC. Raines LN, et al. Among authors: huang sc. Cancer Cell. 2021 Jul 12;39(7):907-909. doi: 10.1016/j.ccell.2021.06.006. Cancer Cell. 2021. PMID: 34256906 Free article.
PERK is a critical metabolic hub for immunosuppressive function in macrophages.
Raines LN, Zhao H, Wang Y, Chen HY, Gallart-Ayala H, Hsueh PC, Cao W, Koh Y, Alamonte-Loya A, Liu PS, Ivanisevic J, Lio CJ, Ho PC, Huang SC. Raines LN, et al. Among authors: huang sc. Nat Immunol. 2022 Mar;23(3):431-445. doi: 10.1038/s41590-022-01145-x. Epub 2022 Feb 28. Nat Immunol. 2022. PMID: 35228694 Free PMC article.
Control of immune cell function by the unfolded protein response.
Di Conza G, Ho PC, Cubillos-Ruiz JR, Huang SC. Di Conza G, et al. Among authors: huang sc. Nat Rev Immunol. 2023 Sep;23(9):546-562. doi: 10.1038/s41577-023-00838-0. Epub 2023 Feb 8. Nat Rev Immunol. 2023. PMID: 36755160 Review.
2,190 results