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Prevention of skin carcinogenesis by the β-blocker carvedilol.
Chang A, Yeung S, Thakkar A, Huang KM, Liu MM, Kanassatega RS, Parsa C, Orlando R, Jackson EK, Andresen BT, Huang Y. Chang A, et al. Among authors: huang km, huang y. Cancer Prev Res (Phila). 2015 Jan;8(1):27-36. doi: 10.1158/1940-6207.CAPR-14-0193. Epub 2014 Nov 3. Cancer Prev Res (Phila). 2015. PMID: 25367979 Free PMC article.
Kidney toxicity of the BRAF-kinase inhibitor vemurafenib is driven by off-target ferrochelatase inhibition.
Bai Y, Kim JY, Bisunke B, Jayne LA, Silvaroli JA, Balzer MS, Gandhi M, Huang KM, Sander V, Prosek J, Cianciolo RE, Baker SD, Sparreboom A, Jhaveri KD, Susztak K, Bajwa A, Pabla NS. Bai Y, et al. Among authors: huang km. Kidney Int. 2021 Dec;100(6):1214-1226. doi: 10.1016/j.kint.2021.08.022. Epub 2021 Sep 15. Kidney Int. 2021. PMID: 34534550 Free PMC article.
TP-0903 is active in models of drug-resistant acute myeloid leukemia.
Jeon JY, Buelow DR, Garrison DA, Niu M, Eisenmann ED, Huang KM, Zavorka Thomas ME, Weber RH, Whatcott CJ, Warner SL, Orwick SJ, Carmichael B, Stahl E, Brinton LT, Lapalombella R, Blachly JS, Hertlein E, Byrd JC, Bhatnagar B, Baker SD. Jeon JY, et al. Among authors: huang km. JCI Insight. 2020 Dec 3;5(23):e140169. doi: 10.1172/jci.insight.140169. JCI Insight. 2020. PMID: 33268594 Free PMC article.
Role of SLC transporters in toxicity induced by anticancer drugs.
Huang KM, Uddin ME, DiGiacomo D, Lustberg MB, Hu S, Sparreboom A. Huang KM, et al. Expert Opin Drug Metab Toxicol. 2020 Jun;16(6):493-506. doi: 10.1080/17425255.2020.1755253. Epub 2020 Apr 26. Expert Opin Drug Metab Toxicol. 2020. PMID: 32276560 Free PMC article. Review.
171 results