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Cas13d knockdown of lung protease Ctsl prevents and treats SARS-CoV-2 infection.
Cui Z, Zeng C, Huang F, Yuan F, Yan J, Zhao Y, Zhou Y, Hankey W, Jin VX, Huang J, Staats HF, Everitt JI, Sempowski GD, Wang H, Dong Y, Liu SL, Wang Q. Cui Z, et al. Among authors: huang f, huang j. Nat Chem Biol. 2022 Oct;18(10):1056-1064. doi: 10.1038/s41589-022-01094-4. Epub 2022 Jul 25. Nat Chem Biol. 2022. PMID: 35879545 Free PMC article.
Diverse AR-V7 cistromes in castration-resistant prostate cancer are governed by HoxB13.
Chen Z, Wu D, Thomas-Ahner JM, Lu C, Zhao P, Zhang Q, Geraghty C, Yan PS, Hankey W, Sunkel B, Cheng X, Antonarakis ES, Wang QE, Liu Z, Huang TH, Jin VX, Clinton SK, Luo J, Huang J, Wang Q. Chen Z, et al. Among authors: huang th, huang j. Proc Natl Acad Sci U S A. 2018 Jun 26;115(26):6810-6815. doi: 10.1073/pnas.1718811115. Epub 2018 May 29. Proc Natl Acad Sci U S A. 2018. PMID: 29844167 Free PMC article.
Phosphorylated MED1 links transcription recycling and cancer growth.
Chen Z, Ye Z, Soccio RE, Nakadai T, Hankey W, Zhao Y, Huang F, Yuan F, Wang H, Cui Z, Sunkel B, Wu D, Dzeng RK, Thomas-Ahner JM, Huang THM, Clinton SK, Huang J, Lazar MA, Jin VX, Roeder RG, Wang Q. Chen Z, et al. Among authors: huang thm, huang f, huang j. Nucleic Acids Res. 2022 May 6;50(8):4450-4463. doi: 10.1093/nar/gkac246. Nucleic Acids Res. 2022. PMID: 35394046 Free PMC article.
Targeting cellular heterogeneity with CXCR2 blockade for the treatment of therapy-resistant prostate cancer.
Li Y, He Y, Butler W, Xu L, Chang Y, Lei K, Zhang H, Zhou Y, Gao AC, Zhang Q, Taylor DG, Cheng D, Farber-Katz S, Karam R, Landrith T, Li B, Wu S, Hsuan V, Yang Q, Hu H, Chen X, Flowers M, McCall SJ, Lee JK, Smith BA, Park JW, Goldstein AS, Witte ON, Wang Q, Rettig MB, Armstrong AJ, Cheng Q, Huang J. Li Y, et al. Among authors: huang j. Sci Transl Med. 2019 Dec 4;11(521):eaax0428. doi: 10.1126/scitranslmed.aax0428. Sci Transl Med. 2019. PMID: 31801883 Free PMC article.
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