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CD4+ T-cell epitope-based heterologous prime-boost vaccination potentiates anti-tumor immunity and PD-1/PD-L1 immunotherapy.
Xiao M, Xie L, Cao G, Lei S, Wang P, Wei Z, Luo Y, Fang J, Yang X, Huang Q, Xu L, Guo J, Wen S, Wang Z, Wu Q, Tang J, Wang L, Chen X, Chen C, Zhang Y, Yao W, Ye J, He R, Huang J, Ye L. Xiao M, et al. Among authors: huang q, huang j. J Immunother Cancer. 2022 May;10(5):e004022. doi: 10.1136/jitc-2021-004022. J Immunother Cancer. 2022. PMID: 35580929 Free PMC article.
The histone methyltransferase EZH2 primes the early differentiation of follicular helper T cells during acute viral infection.
Chen X, Cao G, Wu J, Wang X, Pan Z, Gao J, Tian Q, Xu L, Li Z, Hao Y, Huang Q, Wang P, Xiao M, Xie L, Tang S, Liu Z, Hu L, Tang J, He R, Wang L, Zhou X, Wu Y, Chen M, Sun B, Zhu B, Huang J, Ye L. Chen X, et al. Among authors: huang q, huang j. Cell Mol Immunol. 2020 Mar;17(3):247-260. doi: 10.1038/s41423-019-0219-z. Epub 2019 Mar 6. Cell Mol Immunol. 2020. PMID: 30842630 Free PMC article.
TCR-pMHC bond conformation controls TCR ligand discrimination.
Sasmal DK, Feng W, Roy S, Leung P, He Y, Cai C, Cao G, Lian H, Qin J, Hui E, Schreiber H, Adams EJ, Huang J. Sasmal DK, et al. Among authors: huang j. Cell Mol Immunol. 2020 Mar;17(3):203-217. doi: 10.1038/s41423-019-0273-6. Epub 2019 Sep 17. Cell Mol Immunol. 2020. PMID: 31530899 Free PMC article.
Multimodal probing of T-cell recognition with hexapod heterostructures.
Huang X, Meng L, Cao G, Prominski A, Hu Y, Yang C, Chen M, Shi J, Gallagher C, Cao T, Yue J, Huang J, Tian B. Huang X, et al. Among authors: huang j. Nat Methods. 2024 May;21(5):857-867. doi: 10.1038/s41592-023-02165-7. Epub 2024 Feb 19. Nat Methods. 2024. PMID: 38374262
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