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Efficacy and safety of minimally invasive surgery with thrombolysis in intracerebral haemorrhage evacuation (MISTIE III): a randomised, controlled, open-label, blinded endpoint phase 3 trial.
Hanley DF, Thompson RE, Rosenblum M, Yenokyan G, Lane K, McBee N, Mayo SW, Bistran-Hall AJ, Gandhi D, Mould WA, Ullman N, Ali H, Carhuapoma JR, Kase CS, Lees KR, Dawson J, Wilson A, Betz JF, Sugar EA, Hao Y, Avadhani R, Caron JL, Harrigan MR, Carlson AP, Bulters D, LeDoux D, Huang J, Cobb C, Gupta G, Kitagawa R, Chicoine MR, Patel H, Dodd R, Camarata PJ, Wolfe S, Stadnik A, Money PL, Mitchell P, Sarabia R, Harnof S, Barzo P, Unterberg A, Teitelbaum JS, Wang W, Anderson CS, Mendelow AD, Gregson B, Janis S, Vespa P, Ziai W, Zuccarello M, Awad IA; MISTIE III Investigators. Hanley DF, et al. Among authors: huang j. Lancet. 2019 Mar 9;393(10175):1021-1032. doi: 10.1016/S0140-6736(19)30195-3. Epub 2019 Feb 7. Lancet. 2019. PMID: 30739747 Free PMC article. Clinical Trial.
Minimally invasive surgery plus recombinant tissue-type plasminogen activator for intracerebral hemorrhage evacuation decreases perihematomal edema.
Mould WA, Carhuapoma JR, Muschelli J, Lane K, Morgan TC, McBee NA, Bistran-Hall AJ, Ullman NL, Vespa P, Martin NA, Awad I, Zuccarello M, Hanley DF; MISTIE Investigators. Mould WA, et al. Stroke. 2013 Mar;44(3):627-34. doi: 10.1161/STROKEAHA.111.000411. Epub 2013 Feb 7. Stroke. 2013. PMID: 23391763 Free PMC article. Clinical Trial.
Safety and efficacy of minimally invasive surgery plus alteplase in intracerebral haemorrhage evacuation (MISTIE): a randomised, controlled, open-label, phase 2 trial.
Hanley DF, Thompson RE, Muschelli J, Rosenblum M, McBee N, Lane K, Bistran-Hall AJ, Mayo SW, Keyl P, Gandhi D, Morgan TC, Ullman N, Mould WA, Carhuapoma JR, Kase C, Ziai W, Thompson CB, Yenokyan G, Huang E, Broaddus WC, Graham RS, Aldrich EF, Dodd R, Wijman C, Caron JL, Huang J, Camarata P, Mendelow AD, Gregson B, Janis S, Vespa P, Martin N, Awad I, Zuccarello M; MISTIE Investigators. Hanley DF, et al. Among authors: huang e, huang j. Lancet Neurol. 2016 Nov;15(12):1228-1237. doi: 10.1016/S1474-4422(16)30234-4. Epub 2016 Oct 11. Lancet Neurol. 2016. PMID: 27751554 Free PMC article. Clinical Trial.
Permanent CSF shunting after intraventricular hemorrhage in the CLEAR III trial.
Murthy SB, Awad I, Harnof S, Aldrich F, Harrigan M, Jallo J, Caron JL, Huang J, Camarata P, Lara LR, Dlugash R, McBee N, Eslami V, Hanley DF, Ziai WC; CLEAR III Trial Investigators. Murthy SB, et al. Among authors: huang j. Neurology. 2017 Jul 25;89(4):355-362. doi: 10.1212/WNL.0000000000004155. Epub 2017 Jun 28. Neurology. 2017. PMID: 28659429 Free PMC article. Clinical Trial.
Intracranial Hypertension and Cerebral Perfusion Pressure Insults in Adult Hypertensive Intraventricular Hemorrhage: Occurrence and Associations With Outcome.
Ziai WC, Thompson CB, Mayo S, McBee N, Freeman WD, Dlugash R, Ullman N, Hao Y, Lane K, Awad I, Hanley DF; Clot Lysis: Evaluating Accelerated Resolution of Intraventricular Hemorrhage (CLEAR III) Investigators. Ziai WC, et al. Crit Care Med. 2019 Aug;47(8):1125-1134. doi: 10.1097/CCM.0000000000003848. Crit Care Med. 2019. PMID: 31162192 Free PMC article. Clinical Trial.
Improving medical student recruitment to neurosurgery.
Lubelski D, Xiao R, Mukherjee D, Ashley WW, Witham T, Brem H, Huang J, Wolfe SQ. Lubelski D, et al. Among authors: huang j. J Neurosurg. 2019 Aug 9:1-7. doi: 10.3171/2019.5.JNS1987. Online ahead of print. J Neurosurg. 2019. PMID: 31398709
Longitudinal transcriptomics define the stages of myeloid activation in the living human brain after intracerebral hemorrhage.
Askenase MH, Goods BA, Beatty HE, Steinschneider AF, Velazquez SE, Osherov A, Landreneau MJ, Carroll SL, Tran TB, Avram VS, Drake RS, Gatter GJ, Massey JA, Karuppagounder SS, Ratan RR, Matouk CC, Sheth KN, Ziai WC, Parry-Jones AR, Awad IA, Zuccarello M, Thompson RE, Dawson J, Hanley DF, Love JC, Shalek AK, Sansing LH; MISTIE III Consortium; ICHseq investigators; ICHseq Investigators MISTIE III Investigators. Askenase MH, et al. Sci Immunol. 2021 Feb 19;6(56):eabd6279. doi: 10.1126/sciimmunol.abd6279. Epub 2021 Feb 19. Sci Immunol. 2021. PMID: 33891558 Free PMC article.
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