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Taiwan Biobank: A rich biomedical research database of the Taiwanese population.
Feng YA, Chen CY, Chen TT, Kuo PH, Hsu YH, Yang HI, Chen WJ, Su MW, Chu HW, Shen CY, Ge T, Huang H, Lin YF. Feng YA, et al. Among authors: huang h. Cell Genom. 2022 Oct 12;2(11):100197. doi: 10.1016/j.xgen.2022.100197. eCollection 2022 Nov 9. Cell Genom. 2022. PMID: 36776991 Free PMC article.
Genome-wide Association Studies in Ancestrally Diverse Populations: Opportunities, Methods, Pitfalls, and Recommendations.
Peterson RE, Kuchenbaecker K, Walters RK, Chen CY, Popejoy AB, Periyasamy S, Lam M, Iyegbe C, Strawbridge RJ, Brick L, Carey CE, Martin AR, Meyers JL, Su J, Chen J, Edwards AC, Kalungi A, Koen N, Majara L, Schwarz E, Smoller JW, Stahl EA, Sullivan PF, Vassos E, Mowry B, Prieto ML, Cuellar-Barboza A, Bigdeli TB, Edenberg HJ, Huang H, Duncan LE. Peterson RE, et al. Among authors: huang h. Cell. 2019 Oct 17;179(3):589-603. doi: 10.1016/j.cell.2019.08.051. Epub 2019 Oct 10. Cell. 2019. PMID: 31607513 Free PMC article. Review.
Comparative genetic architectures of schizophrenia in East Asian and European populations.
Lam M, Chen CY, Li Z, Martin AR, Bryois J, Ma X, Gaspar H, Ikeda M, Benyamin B, Brown BC, Liu R, Zhou W, Guan L, Kamatani Y, Kim SW, Kubo M, Kusumawardhani AAAA, Liu CM, Ma H, Periyasamy S, Takahashi A, Xu Z, Yu H, Zhu F; Schizophrenia Working Group of the Psychiatric Genomics Consortium; Indonesia Schizophrenia Consortium; Genetic REsearch on schizophreniA neTwork-China and the Netherlands (GREAT-CN); Chen WJ, Faraone S, Glatt SJ, He L, Hyman SE, Hwu HG, McCarroll SA, Neale BM, Sklar P, Wildenauer DB, Yu X, Zhang D, Mowry BJ, Lee J, Holmans P, Xu S, Sullivan PF, Ripke S, O'Donovan MC, Daly MJ, Qin S, Sham P, Iwata N, Hong KS, Schwab SG, Yue W, Tsuang M, Liu J, Ma X, Kahn RS, Shi Y, Huang H. Lam M, et al. Among authors: huang h. Nat Genet. 2019 Dec;51(12):1670-1678. doi: 10.1038/s41588-019-0512-x. Epub 2019 Nov 18. Nat Genet. 2019. PMID: 31740837 Free PMC article.
Identifying nootropic drug targets via large-scale cognitive GWAS and transcriptomics.
Lam M, Chen CY, Ge T, Xia Y, Hill DW, Trampush JW, Yu J, Knowles E, Davies G, Stahl EA, Huckins L, Liewald DC, Djurovic S, Melle I, Christoforou A, Reinvang I, DeRosse P, Lundervold AJ, Steen VM, Espeseth T, Räikkönen K, Widen E, Palotie A, Eriksson JG, Giegling I, Konte B, Hartmann AM, Roussos P, Giakoumaki S, Burdick KE, Payton A, Ollier W, Chiba-Falek O, Koltai DC, Need AC, Cirulli ET, Voineskos AN, Stefanis NC, Avramopoulos D, Hatzimanolis A, Smyrnis N, Bilder RM, Freimer NB, Cannon TD, London E, Poldrack RA, Sabb FW, Congdon E, Conley ED, Scult MA, Dickinson D, Straub RE, Donohoe G, Morris D, Corvin A, Gill M, Hariri AR, Weinberger DR, Pendleton N, Bitsios P, Rujescu D, Lahti J, Le Hellard S, Keller MC, Andreassen OA, Deary IJ, Glahn DC, Huang H, Liu C, Malhotra AK, Lencz T. Lam M, et al. Among authors: huang h. Neuropsychopharmacology. 2021 Sep;46(10):1788-1801. doi: 10.1038/s41386-021-01023-4. Epub 2021 May 25. Neuropsychopharmacology. 2021. PMID: 34035472 Free PMC article.
A Comparison of Ten Polygenic Score Methods for Psychiatric Disorders Applied Across Multiple Cohorts.
Ni G, Zeng J, Revez JA, Wang Y, Zheng Z, Ge T, Restuadi R, Kiewa J, Nyholt DR, Coleman JRI, Smoller JW; Schizophrenia Working Group of the Psychiatric Genomics Consortium; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; Yang J, Visscher PM, Wray NR. Ni G, et al. Biol Psychiatry. 2021 Nov 1;90(9):611-620. doi: 10.1016/j.biopsych.2021.04.018. Epub 2021 May 4. Biol Psychiatry. 2021. PMID: 34304866 Free PMC article.
Mapping genomic loci implicates genes and synaptic biology in schizophrenia.
Trubetskoy V, Pardiñas AF, Qi T, Panagiotaropoulou G, Awasthi S, Bigdeli TB, Bryois J, Chen CY, Dennison CA, Hall LS, Lam M, Watanabe K, Frei O, Ge T, Harwood JC, Koopmans F, Magnusson S, Richards AL, Sidorenko J, Wu Y, Zeng J, Grove J, Kim M, Li Z, Voloudakis G, Zhang W, Adams M, Agartz I, Atkinson EG, Agerbo E, Al Eissa M, Albus M, Alexander M, Alizadeh BZ, Alptekin K, Als TD, Amin F, Arolt V, Arrojo M, Athanasiu L, Azevedo MH, Bacanu SA, Bass NJ, Begemann M, Belliveau RA, Bene J, Benyamin B, Bergen SE, Blasi G, Bobes J, Bonassi S, Braun A, Bressan RA, Bromet EJ, Bruggeman R, Buckley PF, Buckner RL, Bybjerg-Grauholm J, Cahn W, Cairns MJ, Calkins ME, Carr VJ, Castle D, Catts SV, Chambert KD, Chan RCK, Chaumette B, Cheng W, Cheung EFC, Chong SA, Cohen D, Consoli A, Cordeiro Q, Costas J, Curtis C, Davidson M, Davis KL, de Haan L, Degenhardt F, DeLisi LE, Demontis D, Dickerson F, Dikeos D, Dinan T, Djurovic S, Duan J, Ducci G, Dudbridge F, Eriksson JG, Fañanás L, Faraone SV, Fiorentino A, Forstner A, Frank J, Freimer NB, Fromer M, Frustaci A, Gadelha A, Genovese G, Gershon ES, Giannitelli M, Giegling I, Giusti-Rodríguez P, Godard S, Goldstein JI, González Peñas J, González-Pinto A, … See abstract for full author list ➔ Trubetskoy V, et al. Among authors: huang h. Nature. 2022 Apr;604(7906):502-508. doi: 10.1038/s41586-022-04434-5. Epub 2022 Apr 8. Nature. 2022. PMID: 35396580 Free PMC article.
Improving polygenic prediction in ancestrally diverse populations.
Ruan Y, Lin YF, Feng YA, Chen CY, Lam M, Guo Z; Stanley Global Asia Initiatives; He L, Sawa A, Martin AR, Qin S, Huang H, Ge T. Ruan Y, et al. Among authors: huang h. Nat Genet. 2022 May;54(5):573-580. doi: 10.1038/s41588-022-01054-7. Epub 2022 May 5. Nat Genet. 2022. PMID: 35513724 Free PMC article.
Development and validation of a trans-ancestry polygenic risk score for type 2 diabetes in diverse populations.
Ge T, Irvin MR, Patki A, Srinivasasainagendra V, Lin YF, Tiwari HK, Armstrong ND, Benoit B, Chen CY, Choi KW, Cimino JJ, Davis BH, Dikilitas O, Etheridge B, Feng YA, Gainer V, Huang H, Jarvik GP, Kachulis C, Kenny EE, Khan A, Kiryluk K, Kottyan L, Kullo IJ, Lange C, Lennon N, Leong A, Malolepsza E, Miles AD, Murphy S, Namjou B, Narayan R, O'Connor MJ, Pacheco JA, Perez E, Rasmussen-Torvik LJ, Rosenthal EA, Schaid D, Stamou M, Udler MS, Wei WQ, Weiss ST, Ng MCY, Smoller JW, Lebo MS, Meigs JB, Limdi NA, Karlson EW. Ge T, et al. Among authors: huang h. Genome Med. 2022 Jun 29;14(1):70. doi: 10.1186/s13073-022-01074-2. Genome Med. 2022. PMID: 35765100 Free PMC article.
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