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RUNX represses Pmp22 to drive neurofibromagenesis.
Hall A, Choi K, Liu W, Rose J, Zhao C, Yu Y, Na Y, Cai Y, Coover RA, Lin Y, Dombi E, Kim M, Levanon D, Groner Y, Boscolo E, Pan D, Liu PP, Lu QR, Ratner N, Huang G, Wu J. Hall A, et al. Among authors: huang g. Sci Adv. 2019 Apr 24;5(4):eaau8389. doi: 10.1126/sciadv.aau8389. eCollection 2019 Apr. Sci Adv. 2019. PMID: 31032403 Free PMC article.
Runx1: a new driver in neurofibromagenesis.
Wu J, Huang G, Ratner N. Wu J, et al. Among authors: huang g. Oncoscience. 2015 Nov 17;2(11):904-5. doi: 10.18632/oncoscience.266. eCollection 2015. Oncoscience. 2015. PMID: 26697518 Free PMC article. No abstract available.
Insertional Mutagenesis Identifies a STAT3/Arid1b/β-catenin Pathway Driving Neurofibroma Initiation.
Wu J, Keng VW, Patmore DM, Kendall JJ, Patel AV, Jousma E, Jessen WJ, Choi K, Tschida BR, Silverstein KA, Fan D, Schwartz EB, Fuchs JR, Zou Y, Kim MO, Dombi E, Levy DE, Huang G, Cancelas JA, Stemmer-Rachamimov AO, Spinner RJ, Largaespada DA, Ratner N. Wu J, et al. Among authors: huang g. Cell Rep. 2016 Mar 1;14(8):1979-90. doi: 10.1016/j.celrep.2016.01.074. Epub 2016 Feb 18. Cell Rep. 2016. PMID: 26904939 Free PMC article.
Transcription factor RUNX1 promotes survival of acute myeloid leukemia cells.
Goyama S, Schibler J, Cunningham L, Zhang Y, Rao Y, Nishimoto N, Nakagawa M, Olsson A, Wunderlich M, Link KA, Mizukawa B, Grimes HL, Kurokawa M, Liu PP, Huang G, Mulloy JC. Goyama S, et al. Among authors: huang g. J Clin Invest. 2013 Sep;123(9):3876-88. doi: 10.1172/JCI68557. Epub 2013 Aug 27. J Clin Invest. 2013. PMID: 23979164 Free PMC article.
Defective transcription elongation in a subset of cancers confers immunotherapy resistance.
Modur V, Singh N, Mohanty V, Chung E, Muhammad B, Choi K, Chen X, Chetal K, Ratner N, Salomonis N, Weirauch MT, Waltz S, Huang G, Privette-Vinnedge L, Park JS, Janssen EM, Komurov K. Modur V, et al. Among authors: huang g. Nat Commun. 2018 Oct 23;9(1):4410. doi: 10.1038/s41467-018-06810-0. Nat Commun. 2018. PMID: 30353012 Free PMC article.
Adaptive responses to mTOR gene targeting in hematopoietic stem cells reveal a proliferative mechanism evasive to mTOR inhibition.
Fan C, Zhao C, Zhang F, Kesarwani M, Tu Z, Cai X, Davis AK, Xu L, Hochstetler CL, Chen X, Guo F, Huang G, Azam M, Tian W, Lu QR, Zheng Y. Fan C, et al. Among authors: huang g. Proc Natl Acad Sci U S A. 2021 Jan 5;118(1):e2020102118. doi: 10.1073/pnas.2020102118. Epub 2020 Dec 21. Proc Natl Acad Sci U S A. 2021. PMID: 33443202 Free PMC article.
Pathobiological Pseudohypoxia as a Putative Mechanism Underlying Myelodysplastic Syndromes.
Hayashi Y, Zhang Y, Yokota A, Yan X, Liu J, Choi K, Li B, Sashida G, Peng Y, Xu Z, Huang R, Zhang L, Freudiger GM, Wang J, Dong Y, Zhou Y, Wang J, Wu L, Bu J, Chen A, Zhao X, Sun X, Chetal K, Olsson A, Watanabe M, Romick-Rosendale LE, Harada H, Shih LY, Tse W, Bridges JP, Caligiuri MA, Huang T, Zheng Y, Witte DP, Wang QF, Qu CK, Salomonis N, Grimes HL, Nimer SD, Xiao Z, Huang G. Hayashi Y, et al. Among authors: huang r, huang t, huang g. Cancer Discov. 2018 Nov;8(11):1438-1457. doi: 10.1158/2159-8290.CD-17-1203. Epub 2018 Aug 23. Cancer Discov. 2018. PMID: 30139811 Free PMC article.
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