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Benralizumab Normalizes Sputum Eosinophilia in Severe Asthma Uncontrolled by Anti-IL-5 Antibodies: A Single-Blind, Placebo-controlled Clinical Trial.
Mukherjee M, Huang C, Venegas-Garrido C, Zhang K, Bhalla A, Ju X, O'Byrne PM, Svenningsen S, Sehmi R, Nair P. Mukherjee M, et al. Among authors: huang c. Am J Respir Crit Care Med. 2023 Dec 15;208(12):1330-1335. doi: 10.1164/rccm.202308-1413LE. Am J Respir Crit Care Med. 2023. PMID: 37824744 Clinical Trial. No abstract available.
Increased numbers of activated group 2 innate lymphoid cells in the airways of patients with severe asthma and persistent airway eosinophilia.
Smith SG, Chen R, Kjarsgaard M, Huang C, Oliveria JP, O'Byrne PM, Gauvreau GM, Boulet LP, Lemiere C, Martin J, Nair P, Sehmi R. Smith SG, et al. Among authors: huang c. J Allergy Clin Immunol. 2016 Jan;137(1):75-86.e8. doi: 10.1016/j.jaci.2015.05.037. Epub 2015 Jul 17. J Allergy Clin Immunol. 2016. PMID: 26194544
Sputum autoantibodies in patients with severe eosinophilic asthma.
Mukherjee M, Bulir DC, Radford K, Kjarsgaard M, Huang CM, Jacobsen EA, Ochkur SI, Catuneanu A, Lamothe-Kipnes H, Mahony J, Lee JJ, Lacy P, Nair PK. Mukherjee M, et al. Among authors: huang cm. J Allergy Clin Immunol. 2018 Apr;141(4):1269-1279. doi: 10.1016/j.jaci.2017.06.033. Epub 2017 Jul 24. J Allergy Clin Immunol. 2018. PMID: 28751233
Benralizumab attenuates airway eosinophilia in prednisone-dependent asthma.
Sehmi R, Lim HF, Mukherjee M, Huang C, Radford K, Newbold P, Boulet LP, Dorscheid D, Martin JG, Nair P. Sehmi R, et al. Among authors: huang c. J Allergy Clin Immunol. 2018 Apr;141(4):1529-1532.e8. doi: 10.1016/j.jaci.2018.01.008. Epub 2018 Jan 31. J Allergy Clin Immunol. 2018. PMID: 29382593 Clinical Trial. No abstract available.
Omalizumab in patients with severe asthma and persistent sputum eosinophilia.
Mukherjee M, Kjarsgaard M, Radford K, Huang C, Leigh R, Dorscheid DR, Lemiere C, Boulet LP, Waserman S, Martin J, Nair P. Mukherjee M, et al. Among authors: huang c. Allergy Asthma Clin Immunol. 2019 Apr 3;15:21. doi: 10.1186/s13223-019-0337-2. eCollection 2019. Allergy Asthma Clin Immunol. 2019. PMID: 30988677 Free PMC article.
Suboptimal treatment response to anti-IL-5 monoclonal antibodies in severe eosinophilic asthmatics with airway autoimmune phenomena.
Mukherjee M, Forero DF, Tran S, Boulay ME, Bertrand M, Bhalla A, Cherukat J, Al-Hayyan H, Ayoub A, Revill SD, Javkar T, Radford K, Kjarsgaard M, Huang C, Dvorkin-Gheva A, Ask K, Olivenstein R, Dendukuri N, Lemiere C, Boulet LP, Martin JG, Nair P. Mukherjee M, et al. Among authors: huang c. Eur Respir J. 2020 Oct 8;56(4):2000117. doi: 10.1183/13993003.00117-2020. Print 2020 Oct. Eur Respir J. 2020. PMID: 32444405 Free article.
Asthma exacerbations on benralizumab are largely non-eosinophilic.
Poznanski SM, Mukherjee M, Zhao N, Huang C, Radford K, Ashkar AA, Nair P. Poznanski SM, et al. Among authors: huang c. Allergy. 2021 Jan;76(1):375-379. doi: 10.1111/all.14514. Epub 2020 Aug 7. Allergy. 2021. PMID: 32767484 No abstract available.
Effect of anti-IL-5 biologics on weight and body mass index.
Cusack RP, Huang C, LaVigne N, Satia I, Nair P, O'Byrne PM. Cusack RP, et al. Among authors: huang c. Allergy. 2021 Sep;76(9):2913-2916. doi: 10.1111/all.14956. Epub 2021 Jun 7. Allergy. 2021. PMID: 34028047 No abstract available.
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