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Increase in acid sphingomyelinase level in human retinal endothelial cells and CD34+ circulating angiogenic cells isolated from diabetic individuals is associated with dysfunctional retinal vasculature and vascular repair process in diabetes.
Kady N, Yan Y, Salazar T, Wang Q, Chakravarthy H, Huang C, Beli E, Navitskaya S, Grant M, Busik J. Kady N, et al. Among authors: huang c. J Clin Lipidol. 2017 May-Jun;11(3):694-703. doi: 10.1016/j.jacl.2017.03.007. Epub 2017 Mar 30. J Clin Lipidol. 2017. PMID: 28457994 Free PMC article.
ELOVL4-Mediated Production of Very Long-Chain Ceramides Stabilizes Tight Junctions and Prevents Diabetes-Induced Retinal Vascular Permeability.
Kady NM, Liu X, Lydic TA, Syed MH, Navitskaya S, Wang Q, Hammer SS, O'Reilly S, Huang C, Seregin SS, Amalfitano A, Chiodo VA, Boye SL, Hauswirth WW, Antonetti DA, Busik JV. Kady NM, et al. Among authors: huang c. Diabetes. 2018 Apr;67(4):769-781. doi: 10.2337/db17-1034. Epub 2018 Jan 23. Diabetes. 2018. PMID: 29362226 Free PMC article.
Mitochondrial Ceramide Effects on the Retinal Pigment Epithelium in Diabetes.
Levitsky Y, Hammer SS, Fisher KP, Huang C, Gentles TL, Pegouske DJ, Xi C, Lydic TA, Busik JV, Proshlyakov DA. Levitsky Y, et al. Among authors: huang c. Int J Mol Sci. 2020 May 28;21(11):3830. doi: 10.3390/ijms21113830. Int J Mol Sci. 2020. PMID: 32481596 Free PMC article.
Specific mesoderm subset derived from human pluripotent stem cells ameliorates microvascular pathology in type 2 diabetic mice.
Gil CH, Chakraborty D, Vieira CP, Prasain N, Li Calzi S, Fortmann SD, Hu P, Banno K, Jamal M, Huang C, Sielski MS, Lin Y, Huang X, Dupont MD, Floyd JL, Prasad R, Longhini ALF, McGill TJ, Chung HM, Murphy MP, Kotton DN, Boulton ME, Yoder MC, Grant MB. Gil CH, et al. Among authors: huang c, huang x. Sci Adv. 2022 Mar 4;8(9):eabm5559. doi: 10.1126/sciadv.abm5559. Epub 2022 Mar 4. Sci Adv. 2022. PMID: 35245116 Free PMC article.
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