Hua X - Search Results

1

Bispecific and split CAR T cells targeting CD13 and TIM3 eradicate acute myeloid leukemia.

He X, Feng Z, Ma J, Ling S, Cao Y, Gurung B, Wu Y, Katona BW, O'Dwyer KP, Siegel DL, June CH, Hua X. He X, et al. Among authors: hua x. Blood. 2020 Mar 5;135(10):713-723. doi: 10.1182/blood.2019002779. Blood. 2020. PMID: 31951650 Free PMC article.

2

Nuclear cyclin D1/CDK4 kinase regulates CUL4 expression and triggers neoplastic growth via activation of the PRMT5 methyltransferase.

Aggarwal P, Vaites LP, Kim JK, Mellert H, Gurung B, Nakagawa H, Herlyn M, Hua X, Rustgi AK, McMahon SB, Diehl JA. Aggarwal P, et al. Among authors: hua x. Cancer Cell. 2010 Oct 19;18(4):329-40. doi: 10.1016/j.ccr.2010.08.012. Cancer Cell. 2010. PMID: 20951943 Free PMC article.

3

Reversal of preexisting hyperglycemia in diabetic mice by acute deletion of the Men1 gene.

Yang Y, Gurung B, Wu T, Wang H, Stoffers DA, Hua X. Yang Y, et al. Among authors: hua x. Proc Natl Acad Sci U S A. 2010 Nov 23;107(47):20358-63. doi: 10.1073/pnas.1012257107. Epub 2010 Nov 8. Proc Natl Acad Sci U S A. 2010. PMID: 21059956 Free PMC article.

4

The trithorax protein partner menin acts in tandem with EZH2 to suppress C/EBPα and differentiation in MLL-AF9 leukemia.

Thiel AT, Feng Z, Pant DK, Chodosh LA, Hua X. Thiel AT, et al. Among authors: hua x. Haematologica. 2013 Jun;98(6):918-27. doi: 10.3324/haematol.2012.074195. Epub 2013 Jan 24. Haematologica. 2013. PMID: 23349306 Free PMC article.

5

SUMO modification of menin.

Feng ZJ, Gurung B, Jin GH, Yang XL, Hua XX. Feng ZJ, et al. Am J Cancer Res. 2013;3(1):96-106. Epub 2013 Jan 18. Am J Cancer Res. 2013. PMID: 23359867 Free PMC article.

6

Menin epigenetically represses Hedgehog signaling in MEN1 tumor syndrome.

Gurung B, Feng Z, Iwamoto DV, Thiel A, Jin G, Fan CM, Ng JM, Curran T, Hua X. Gurung B, et al. Among authors: hua x. Cancer Res. 2013 Apr 15;73(8):2650-8. doi: 10.1158/0008-5472.CAN-12-3158. Epub 2013 Apr 11. Cancer Res. 2013. PMID: 23580576 Free PMC article.

7

Menin directly represses Gli1 expression independent of canonical Hedgehog signaling.

Gurung B, Feng Z, Hua X. Gurung B, et al. Among authors: hua x. Mol Cancer Res. 2013 Oct;11(10):1215-22. doi: 10.1158/1541-7786.MCR-13-0170. Epub 2013 Aug 8. Mol Cancer Res. 2013. PMID: 23928057 Free PMC article.

8

Menin/PRMT5/hedgehog signaling: a potential target for the treatment of multiple endocrine neoplasia type 1 tumors.

Gurung B, Hua X. Gurung B, et al. Among authors: hua x. Epigenomics. 2013;5(5):469-71. doi: 10.2217/epi.13.47. Epigenomics. 2013. PMID: 24059791 Free PMC article. No abstract available.

9

Menin is required for optimal processing of the microRNA let-7a.

Gurung B, Muhammad AB, Hua X. Gurung B, et al. Among authors: hua x. J Biol Chem. 2014 Apr 4;289(14):9902-8. doi: 10.1074/jbc.M113.520692. Epub 2014 Feb 21. J Biol Chem. 2014. PMID: 24563463 Free PMC article.

10

Harnessing the hidden antitumor power of the MLL-AF4 oncogene to fight leukemia.

Matkar S, Katona BW, Hua X. Matkar S, et al. Among authors: hua x. Cancer Cell. 2014 Apr 14;25(4):411-3. doi: 10.1016/j.ccr.2014.03.028. Cancer Cell. 2014. PMID: 24735921 Free PMC article.

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