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Thrombomodulin domain 1 ameliorates diabetic nephropathy in mice via anti-NF-κB/NLRP3 inflammasome-mediated inflammation, enhancement of NRF2 antioxidant activity and inhibition of apoptosis.
Yang SM, Ka SM, Wu HL, Yeh YC, Kuo CH, Hua KF, Shi GY, Hung YJ, Hsiao FC, Yang SS, Shieh YS, Lin SH, Wei CW, Lee JS, Yang CY, Chen A. Yang SM, et al. Among authors: hua kf. Diabetologia. 2014 Feb;57(2):424-34. doi: 10.1007/s00125-013-3115-6. Epub 2013 Nov 30. Diabetologia. 2014. PMID: 24317792
Osthole improves an accelerated focal segmental glomerulosclerosis model in the early stage by activating the Nrf2 antioxidant pathway and subsequently inhibiting NF-κB-mediated COX-2 expression and apoptosis.
Yang SM, Chan YL, Hua KF, Chang JM, Chen HL, Tsai YJ, Hsu YJ, Chao LK, Feng-Ling Y, Tsai YL, Wu SH, Wang YF, Tsai CL, Chen A, Ka SM. Yang SM, et al. Among authors: hua kf. Free Radic Biol Med. 2014 Aug;73:260-9. doi: 10.1016/j.freeradbiomed.2014.05.009. Epub 2014 May 22. Free Radic Biol Med. 2014. PMID: 24858719
121 results