Hu Z - Search Results

1

CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells.

Kim J, Hu Z, Cai L, Li K, Choi E, Faubert B, Bezwada D, Rodriguez-Canales J, Villalobos P, Lin YF, Ni M, Huffman KE, Girard L, Byers LA, Unsal-Kacmaz K, Peña CG, Heymach JV, Wauters E, Vansteenkiste J, Castrillon DH, Chen BPC, Wistuba I, Lambrechts D, Xu J, Minna JD, DeBerardinis RJ. Kim J, et al. Among authors: hu z. Nature. 2017 Jun 1;546(7656):168-172. doi: 10.1038/nature22359. Epub 2017 May 24. Nature. 2017. PMID: 28538732 Free PMC article.

2

Oxidation of alpha-ketoglutarate is required for reductive carboxylation in cancer cells with mitochondrial defects.

Mullen AR, Hu Z, Shi X, Jiang L, Boroughs LK, Kovacs Z, Boriack R, Rakheja D, Sullivan LB, Linehan WM, Chandel NS, DeBerardinis RJ. Mullen AR, et al. Among authors: hu z. Cell Rep. 2014 Jun 12;7(5):1679-1690. doi: 10.1016/j.celrep.2014.04.037. Epub 2014 May 22. Cell Rep. 2014. PMID: 24857658 Free PMC article.

3

Inhibition of cancer cell proliferation by PPARγ is mediated by a metabolic switch that increases reactive oxygen species levels.

Srivastava N, Kollipara RK, Singh DK, Sudderth J, Hu Z, Nguyen H, Wang S, Humphries CG, Carstens R, Huffman KE, DeBerardinis RJ, Kittler R. Srivastava N, et al. Among authors: hu z. Cell Metab. 2014 Oct 7;20(4):650-61. doi: 10.1016/j.cmet.2014.08.003. Epub 2014 Sep 25. Cell Metab. 2014. PMID: 25264247 Free PMC article.

4

MCT4 defines a glycolytic subtype of pancreatic cancer with poor prognosis and unique metabolic dependencies.

Baek G, Tse YF, Hu Z, Cox D, Buboltz N, McCue P, Yeo CJ, White MA, DeBerardinis RJ, Knudsen ES, Witkiewicz AK. Baek G, et al. Among authors: hu z. Cell Rep. 2014 Dec 24;9(6):2233-49. doi: 10.1016/j.celrep.2014.11.025. Epub 2014 Dec 11. Cell Rep. 2014. PMID: 25497091 Free article.

5

The gut commensal Bacteroides thetaiotaomicron exacerbates enteric infection through modification of the metabolic landscape.

Curtis MM, Hu Z, Klimko C, Narayanan S, Deberardinis R, Sperandio V. Curtis MM, et al. Among authors: hu z. Cell Host Microbe. 2014 Dec 10;16(6):759-69. doi: 10.1016/j.chom.2014.11.005. Cell Host Microbe. 2014. PMID: 25498343 Free PMC article.

6

MAVS, cGAS, and endogenous retroviruses in T-independent B cell responses.

Zeng M, Hu Z, Shi X, Li X, Zhan X, Li XD, Wang J, Choi JH, Wang KW, Purrington T, Tang M, Fina M, DeBerardinis RJ, Moresco EM, Pedersen G, McInerney GM, Karlsson Hedestam GB, Chen ZJ, Beutler B. Zeng M, et al. Among authors: hu z. Science. 2014 Dec 19;346(6216):1486-92. doi: 10.1126/science.346.6216.1486. Science. 2014. PMID: 25525240 Free PMC article. Retracted.

7

Metabolic plasticity maintains proliferation in pyruvate dehydrogenase deficient cells.

Rajagopalan KN, Egnatchik RA, Calvaruso MA, Wasti AT, Padanad MS, Boroughs LK, Ko B, Hensley CT, Acar M, Hu Z, Jiang L, Pascual JM, Scaglioni PP, DeBerardinis RJ. Rajagopalan KN, et al. Among authors: hu z. Cancer Metab. 2015 Jun 29;3:7. doi: 10.1186/s40170-015-0134-4. eCollection 2015. Cancer Metab. 2015. PMID: 26137220 Free PMC article.

8

A nanobuffer reporter library for fine-scale imaging and perturbation of endocytic organelles.

Wang C, Wang Y, Li Y, Bodemann B, Zhao T, Ma X, Huang G, Hu Z, DeBerardinis RJ, White MA, Gao J. Wang C, et al. Among authors: hu z. Nat Commun. 2015 Oct 5;6:8524. doi: 10.1038/ncomms9524. Nat Commun. 2015. PMID: 26437053 Free PMC article.

9

Oxidative stress inhibits distant metastasis by human melanoma cells.

Piskounova E, Agathocleous M, Murphy MM, Hu Z, Huddlestun SE, Zhao Z, Leitch AM, Johnson TM, DeBerardinis RJ, Morrison SJ. Piskounova E, et al. Among authors: hu z. Nature. 2015 Nov 12;527(7577):186-91. doi: 10.1038/nature15726. Epub 2015 Oct 14. Nature. 2015. PMID: 26466563 Free PMC article.

10

NRF2 regulates serine biosynthesis in non-small cell lung cancer.

DeNicola GM, Chen PH, Mullarky E, Sudderth JA, Hu Z, Wu D, Tang H, Xie Y, Asara JM, Huffman KE, Wistuba II, Minna JD, DeBerardinis RJ, Cantley LC. DeNicola GM, et al. Among authors: hu z. Nat Genet. 2015 Dec;47(12):1475-81. doi: 10.1038/ng.3421. Epub 2015 Oct 19. Nat Genet. 2015. PMID: 26482881 Free PMC article.

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