Hu Y - Search Results

1

Acrolein induced DNA damage, mutagenicity and effect on DNA repair.

Tang MS, Wang HT, Hu Y, Chen WS, Akao M, Feng Z, Hu W. Tang MS, et al. Among authors: hu w, hu y. Mol Nutr Food Res. 2011 Sep;55(9):1291-300. doi: 10.1002/mnfr.201100148. Epub 2011 Jun 29. Mol Nutr Food Res. 2011. PMID: 21714128 Free PMC article. Review.

2

Mutagenicity and sequence specificity of acrolein-DNA adducts.

Wang HT, Zhang S, Hu Y, Tang MS. Wang HT, et al. Among authors: hu y. Chem Res Toxicol. 2009 Mar 16;22(3):511-7. doi: 10.1021/tx800369y. Chem Res Toxicol. 2009. PMID: 19146376 Free PMC article.

Previously, we found that the Acr-DNA binding pattern in the human p53 gene coincides with the p53 mutational pattern in CS-related lung cancer; hence, we proposed that Acr is a major lung cancer etiological agent [ Feng , Z. , Hu , W. , Hu , Y. , and Tang , …

Previously, we found that the Acr-DNA binding pattern in the human p53 gene coincides with the p53 mutational pattern in CS-related lung can …

3

Effect of carcinogenic acrolein on DNA repair and mutagenic susceptibility.

Wang HT, Hu Y, Tong D, Huang J, Gu L, Wu XR, Chung FL, Li GM, Tang MS. Wang HT, et al. Among authors: hu y. J Biol Chem. 2012 Apr 6;287(15):12379-86. doi: 10.1074/jbc.M111.329623. Epub 2012 Jan 24. J Biol Chem. 2012. PMID: 22275365 Free PMC article.

4

Acrolein- and 4-Aminobiphenyl-DNA adducts in human bladder mucosa and tumor tissue and their mutagenicity in human urothelial cells.

Lee HW, Wang HT, Weng MW, Hu Y, Chen WS, Chou D, Liu Y, Donin N, Huang WC, Lepor H, Wu XR, Wang H, Beland FA, Tang MS. Lee HW, et al. Among authors: hu y. Oncotarget. 2014 Jun 15;5(11):3526-40. doi: 10.18632/oncotarget.1954. Oncotarget. 2014. PMID: 24939871 Free PMC article.

5

AFB1 hepatocarcinogenesis is via lipid peroxidation that inhibits DNA repair, sensitizes mutation susceptibility and induces aldehyde-DNA adducts at p53 mutational hotspot codon 249.

Weng MW, Lee HW, Choi B, Wang HT, Hu Y, Mehta M, Desai D, Amin S, Zheng Y, Tang MS. Weng MW, et al. Among authors: hu y. Oncotarget. 2017 Mar 14;8(11):18213-18226. doi: 10.18632/oncotarget.15313. Oncotarget. 2017. PMID: 28212554 Free PMC article.

6

DNA damage, DNA repair and carcinogenicity: Tobacco smoke versus electronic cigarette aerosol.

Tang MS, Lee HW, Weng MW, Wang HT, Hu Y, Chen LC, Park SH, Chan HW, Xu J, Wu XR, Wang H, Yang R, Galdane K, Jackson K, Chu A, Halzack E. Tang MS, et al. Among authors: hu y. Mutat Res Rev Mutat Res. 2022 Jan-Jun;789:108409. doi: 10.1016/j.mrrev.2021.108409. Epub 2021 Dec 20. Mutat Res Rev Mutat Res. 2022. PMID: 35690412 Free PMC article. Review.

7

Acrolein is a major cigarette-related lung cancer agent: Preferential binding at p53 mutational hotspots and inhibition of DNA repair.

Feng Z, Hu W, Hu Y, Tang MS. Feng Z, et al. Among authors: hu w, hu y. Proc Natl Acad Sci U S A. 2006 Oct 17;103(42):15404-9. doi: 10.1073/pnas.0607031103. Epub 2006 Oct 9. Proc Natl Acad Sci U S A. 2006. PMID: 17030796 Free PMC article.

8

Aldehydes are the predominant forces inducing DNA damage and inhibiting DNA repair in tobacco smoke carcinogenesis.

Weng MW, Lee HW, Park SH, Hu Y, Wang HT, Chen LC, Rom WN, Huang WC, Lepor H, Wu XR, Yang CS, Tang MS. Weng MW, et al. Among authors: hu y. Proc Natl Acad Sci U S A. 2018 Jul 3;115(27):E6152-E6161. doi: 10.1073/pnas.1804869115. Epub 2018 Jun 18. Proc Natl Acad Sci U S A. 2018. PMID: 29915082 Free PMC article.

9

PAH-DNA adducts in a Chinese population: relationship to PAH exposure, smoking and polymorphisms of metabolic and DNA repair genes.

Hu Y, Li G, Xue X, Zhou Z, Li X, Fu J, Cohen B, Roy N, Li D, Sun J, Nan P, Tang MS, Qu Q. Hu Y, et al. Biomarkers. 2008 Feb;13(1):27-40. doi: 10.1080/13547500701671895. Biomarkers. 2008. PMID: 17896209

10

Arsenic toxicity is enzyme specific and its affects on ligation are not caused by the direct inhibition of DNA repair enzymes.

Hu Y, Su L, Snow ET. Hu Y, et al. Mutat Res. 1998 Sep 11;408(3):203-18. doi: 10.1016/s0921-8777(98)00035-4. Mutat Res. 1998. PMID: 9806419 Free article.

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