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Mannose receptor (CD206) activation in tumor-associated macrophages enhances adaptive and innate antitumor immune responses.
Jaynes JM, Sable R, Ronzetti M, Bautista W, Knotts Z, Abisoye-Ogunniyan A, Li D, Calvo R, Dashnyam M, Singh A, Guerin T, White J, Ravichandran S, Kumar P, Talsania K, Chen V, Ghebremedhin A, Karanam B, Bin Salam A, Amin R, Odzorig T, Aiken T, Nguyen V, Bian Y, Zarif JC, de Groot AE, Mehta M, Fan L, Hu X, Simeonov A, Pate N, Abu-Asab M, Ferrer M, Southall N, Ock CY, Zhao Y, Lopez H, Kozlov S, de Val N, Yates CC, Baljinnyam B, Marugan J, Rudloff U. Jaynes JM, et al. Among authors: hu x. Sci Transl Med. 2020 Feb 12;12(530):eaax6337. doi: 10.1126/scitranslmed.aax6337. Sci Transl Med. 2020. PMID: 32051227 Free PMC article.
Discovery of a Positive Allosteric Modulator of the Thyrotropin Receptor: Potentiation of Thyrotropin-Mediated Preosteoblast Differentiation In Vitro.
Neumann S, Eliseeva E, Boutin A, Barnaeva E, Ferrer M, Southall N, Kim D, Hu X, Morgan SJ, Marugan JJ, Gershengorn MC. Neumann S, et al. Among authors: hu x. J Pharmacol Exp Ther. 2018 Jan;364(1):38-45. doi: 10.1124/jpet.117.244095. Epub 2017 Oct 31. J Pharmacol Exp Ther. 2018. PMID: 29089368 Free PMC article.
Identification of Small Molecule Enhancers of Immunotherapy for Melanoma.
Dextras C, Dashnyam M, Griner LAM, Sundaresan J, Chim B, Yu Z, Vodnala S, Lee CR, Hu X, Southall N, Marugan JJ, Jadhav A, Restifo NP, Acquavella N, Ferrer M, Singh A. Dextras C, et al. Among authors: hu x. Sci Rep. 2020 Mar 30;10(1):5688. doi: 10.1038/s41598-020-62369-1. Sci Rep. 2020. PMID: 32231230 Free PMC article.
Hybrid In Silico Approach Reveals Novel Inhibitors of Multiple SARS-CoV-2 Variants.
Jain S, Talley DC, Baljinnyam B, Choe J, Hanson Q, Zhu W, Xu M, Chen CZ, Zheng W, Hu X, Shen M, Rai G, Hall MD, Simeonov A, Zakharov AV. Jain S, et al. Among authors: hu x. ACS Pharmacol Transl Sci. 2021 Sep 17;4(5):1675-1688. doi: 10.1021/acsptsci.1c00176. eCollection 2021 Oct 8. ACS Pharmacol Transl Sci. 2021. PMID: 34608449 Free PMC article.
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