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Nav1.7 as a chondrocyte regulator and therapeutic target for osteoarthritis.
Fu W, Vasylyev D, Bi Y, Zhang M, Sun G, Khleborodova A, Huang G, Zhao L, Zhou R, Li Y, Liu S, Cai X, He W, Cui M, Zhao X, Hettinghouse A, Good J, Kim E, Strauss E, Leucht P, Schwarzkopf R, Guo EX, Samuels J, Hu W, Attur M, Waxman SG, Liu CJ. Fu W, et al. Among authors: hu w. Nature. 2024 Jan;625(7995):557-565. doi: 10.1038/s41586-023-06888-7. Epub 2024 Jan 3. Nature. 2024. PMID: 38172636 Free PMC article.
14-3-3 epsilon is an intracellular component of TNFR2 receptor complex and its activation protects against osteoarthritis.
Fu W, Hettinghouse A, Chen Y, Hu W, Ding X, Chen M, Ding Y, Mundra J, Song W, Liu R, Yi YS, Attur M, Samuels J, Strauss E, Leucht P, Schwarzkopf R, Liu CJ. Fu W, et al. Among authors: hu w. Ann Rheum Dis. 2021 Dec;80(12):1615-1627. doi: 10.1136/annrheumdis-2021-220000. Epub 2021 Jul 5. Ann Rheum Dis. 2021. PMID: 34226187 Free PMC article.
Foxo4- and Stat3-dependent IL-10 production by progranulin in regulatory T cells restrains inflammatory arthritis.
Fu W, Hu W, Shi L, Mundra JJ, Xiao G, Dustin ML, Liu CJ. Fu W, et al. Among authors: hu w. FASEB J. 2017 Apr;31(4):1354-1367. doi: 10.1096/fj.201601134R. Epub 2016 Dec 23. FASEB J. 2017. PMID: 28011648 Free PMC article.
These findings define a previously unrecognized signaling pathway that underlies IL-10 production by PGRN in T(reg) cells and present new insights into the mechanisms by which PGRN resolves inflammation in inflammatory conditions and autoimmune diseases, particularly inflammatory …
These findings define a previously unrecognized signaling pathway that underlies IL-10 production by PGRN in T(reg) cells and present new in …
Alternative transcription initiation leads to expression of a novel ALK isoform in cancer.
Wiesner T, Lee W, Obenauf AC, Ran L, Murali R, Zhang QF, Wong EW, Hu W, Scott SN, Shah RH, Landa I, Button J, Lailler N, Sboner A, Gao D, Murphy DA, Cao Z, Shukla S, Hollmann TJ, Wang L, Borsu L, Merghoub T, Schwartz GK, Postow MA, Ariyan CE, Fagin JA, Zheng D, Ladanyi M, Busam KJ, Berger MF, Chen Y, Chi P. Wiesner T, et al. Among authors: hu w. Nature. 2015 Oct 15;526(7573):453-7. doi: 10.1038/nature15258. Epub 2015 Oct 7. Nature. 2015. PMID: 26444240 Free PMC article.
Modeling biological and genetic diversity in upper tract urothelial carcinoma with patient derived xenografts.
Kim K, Hu W, Audenet F, Almassi N, Hanrahan AJ, Murray K, Bagrodia A, Wong N, Clinton TN, Dason S, Mohan V, Jebiwott S, Nagar K, Gao J, Penson A, Hughes C, Gordon B, Chen Z, Dong Y, Watson PA, Alvim R, Elzein A, Gao SP, Cocco E, Santin AD, Ostrovnaya I, Hsieh JJ, Sagi I, Pietzak EJ, Hakimi AA, Rosenberg JE, Iyer G, Vargas HA, Scaltriti M, Al-Ahmadie H, Solit DB, Coleman JA. Kim K, et al. Among authors: hu w. Nat Commun. 2020 Apr 24;11(1):1975. doi: 10.1038/s41467-020-15885-7. Nat Commun. 2020. PMID: 32332851 Free PMC article.
Author Correction: FOXA1 repression drives lineage plasticity and immune heterogeneity in bladder cancers with squamous differentiation.
Warrick JI, Hu W, Yamashita H, Walter V, Shuman L, Craig JM, Gellert LL, Castro MAA, Robertson AG, Kuo F, Ostrovnaya I, Sarungbam J, Chen YB, Gopalan A, Sirintrapun SJ, Fine SW, Tickoo SK, Kim K, Thomas J, Karan N, Gao SP, Clinton TN, Lenis AT, Chan TA, Chen Z, Rao M, Hollman TJ, Li Y, Socci ND, Chavan S, Viale A, Mohibullah N, Bochner BH, Pietzak EJ, Teo MY, Iyer G, Rosenberg JE, Bajorin DF, Kaag M, Merrill SB, Joshi M, Adam R, Taylor JA 3rd, Clark PE, Raman JD, Reuter VE, Chen Y, Funt SA, Solit DB, DeGraff DJ, Al-Ahmadie HA. Warrick JI, et al. Among authors: hu w. Nat Commun. 2022 Dec 23;13(1):7920. doi: 10.1038/s41467-022-35644-0. Nat Commun. 2022. PMID: 36564410 Free PMC article. No abstract available.
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