Hsu SD - Search Results

1

Altered Protein Dynamics and a More Reactive Catalytic Cysteine in a Neurodegeneration-associated UCHL1 Mutant.

Kenny S, Lai CH, Chiang TS, Brown K, Hewitt CS, Krabill AD, Chang HT, Wang YS, Flaherty DP, Hsu SD, Das C. Kenny S, et al. Among authors: hsu sd. J Mol Biol. 2024 Feb 15;436(4):168438. doi: 10.1016/j.jmb.2024.168438. Epub 2024 Jan 5. J Mol Biol. 2024. PMID: 38185323

2

The Knotted Protein UCH-L1 Exhibits Partially Unfolded Forms under Native Conditions that Share Common Structural Features with Its Kinetic Folding Intermediates.

Lou SC, Wetzel S, Zhang H, Crone EW, Lee YT, Jackson SE, Hsu SD. Lou SC, et al. Among authors: hsu sd. J Mol Biol. 2016 Jun 5;428(11):2507-2520. doi: 10.1016/j.jmb.2016.04.002. Epub 2016 Apr 8. J Mol Biol. 2016. PMID: 27067109

3

Untying a Protein Knot by Circular Permutation.

Chuang YC, Hu IC, Lyu PC, Hsu SD. Chuang YC, et al. Among authors: hsu sd. J Mol Biol. 2019 Feb 15;431(4):857-863. doi: 10.1016/j.jmb.2019.01.005. Epub 2019 Jan 9. J Mol Biol. 2019. PMID: 30639189

4

Cross-over Loop Cysteine C152 Acts as an Antioxidant to Maintain the Folding Stability and Deubiquitinase Activity of UCH-L1 Under Oxidative Stress.

Puri S, Hsu SD. Puri S, et al. Among authors: hsu sd. J Mol Biol. 2021 Apr 16;433(8):166879. doi: 10.1016/j.jmb.2021.166879. Epub 2021 Feb 19. J Mol Biol. 2021. PMID: 33617897

5

Generation and Characterization of a Spike Glycoprotein Domain A-Specific Neutralizing Single-Chain Variable Fragment against Porcine Epidemic Diarrhea Virus.

Chang CY, Wang YS, Wu JF, Yang TJ, Chang YC, Chae C, Chang HW, Hsu SD. Chang CY, et al. Among authors: hsu sd. Vaccines (Basel). 2021 Jul 29;9(8):833. doi: 10.3390/vaccines9080833. Vaccines (Basel). 2021. PMID: 34451958 Free PMC article.

6

Impacts of Cancer-associated Mutations on the Structure-Activity Relationship of BAP1.

Puri S, Chen SN, Chiu YH, Draczkowski P, Ko KT, Yang TJ, Wang YS, Uchiyama S, Hsu SD. Puri S, et al. Among authors: hsu sd. J Mol Biol. 2022 May 15;434(9):167553. doi: 10.1016/j.jmb.2022.167553. Epub 2022 Mar 19. J Mol Biol. 2022. PMID: 35317997

7

In situ structure and dynamics of an alphacoronavirus spike protein by cryo-ET and cryo-EM.

Huang CY, Draczkowski P, Wang YS, Chang CY, Chien YC, Cheng YH, Wu YM, Wang CH, Chang YC, Chang YC, Yang TJ, Tsai YX, Khoo KH, Chang HW, Hsu SD. Huang CY, et al. Among authors: hsu sd. Nat Commun. 2022 Aug 19;13(1):4877. doi: 10.1038/s41467-022-32588-3. Nat Commun. 2022. PMID: 35986008 Free PMC article.

8

Elucidation of the folding pathway of a circular permutant of topologically knotted YbeA by tryptophan substitutions.

Puri S, Liu CY, Hu IC, Lai CH, Hsu SD, Lyu PC. Puri S, et al. Among authors: hsu sd. Biochem Biophys Res Commun. 2023 Sep 10;672:81-88. doi: 10.1016/j.bbrc.2023.06.021. Epub 2023 Jun 14. Biochem Biophys Res Commun. 2023. PMID: 37343318

9

High Density of N- and O-Glycosylation Shields and Defines the Structural Dynamics of the Intrinsically Disordered Ectodomain of Receptor-type Protein Tyrosine Phosphatase Alpha.

Chien YC, Wang YS, Sridharan D, Kuo CW, Chien CT, Uchihashi T, Kato K, Angata T, Meng TC, Hsu SD, Khoo KH. Chien YC, et al. Among authors: hsu sd. JACS Au. 2023 Jun 13;3(7):1864-1875. doi: 10.1021/jacsau.3c00124. eCollection 2023 Jul 24. JACS Au. 2023. PMID: 37502146 Free PMC article.

10

Structure, dynamics, and stability of the smallest and most complex 7₁ protein knot.

Hsu MF, Sriramoju MK, Lai CH, Chen YR, Huang JS, Ko TP, Huang KF, Hsu SD. Hsu MF, et al. Among authors: hsu sd. J Biol Chem. 2024 Jan;300(1):105553. doi: 10.1016/j.jbc.2023.105553. Epub 2023 Dec 10. J Biol Chem. 2024. PMID: 38072060 Free PMC article.

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