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Development of siRNA payloads to target KRAS-mutant cancer.
Yuan TL, Fellmann C, Lee CS, Ritchie CD, Thapar V, Lee LC, Hsu DJ, Grace D, Carver JO, Zuber J, Luo J, McCormick F, Lowe SW. Yuan TL, et al. Among authors: hsu dj. Cancer Discov. 2014 Oct;4(10):1182-1197. doi: 10.1158/2159-8290.CD-13-0900. Epub 2014 Aug 6. Cancer Discov. 2014. PMID: 25100204 Free PMC article.
Oncogenesis driven by the Ras/Raf pathway requires the SUMO E2 ligase Ubc9.
Yu B, Swatkoski S, Holly A, Lee LC, Giroux V, Lee CS, Hsu D, Smith JL, Yuen G, Yue J, Ann DK, Simpson RM, Creighton CJ, Figg WD, Gucek M, Luo J. Yu B, et al. Proc Natl Acad Sci U S A. 2015 Apr 7;112(14):E1724-33. doi: 10.1073/pnas.1415569112. Epub 2015 Mar 24. Proc Natl Acad Sci U S A. 2015. PMID: 25805818 Free PMC article.
Evolutionarily conserved protein ERH controls CENP-E mRNA splicing and is required for the survival of KRAS mutant cancer cells.
Weng MT, Lee JH, Wei SC, Li Q, Shahamatdar S, Hsu D, Schetter AJ, Swatkoski S, Mannan P, Garfield S, Gucek M, Kim MK, Annunziata CM, Creighton CJ, Emanuele MJ, Harris CC, Sheu JC, Giaccone G, Luo J. Weng MT, et al. Proc Natl Acad Sci U S A. 2012 Dec 26;109(52):E3659-67. doi: 10.1073/pnas.1207673110. Epub 2012 Dec 10. Proc Natl Acad Sci U S A. 2012. PMID: 23236152 Free PMC article.
Threonine fuels glioblastoma through YRDC-mediated codon-biased translational reprogramming.
Wu X, Yuan H, Wu Q, Gao Y, Duan T, Yang K, Huang T, Wang S, Yuan F, Lee D, Taori S, Plute T, Heissel S, Alwaseem H, Isay-Del Viscio M, Molina H, Agnihotri S, Hsu DJ, Zhang N, Rich JN. Wu X, et al. Among authors: hsu dj. Nat Cancer. 2024 Mar 22. doi: 10.1038/s43018-024-00748-7. Online ahead of print. Nat Cancer. 2024. PMID: 38519786
Revealing Excited-State Trajectories on Potential Energy Surfaces with Atomic Resolution in Real Time.
Leshchev D, J S Valentine A, Kim P, Mills AW, Roy S, Chakraborty A, Biasin E, Haldrup K, Hsu DJ, Kirschner MS, Rimmerman D, Chollet M, Glownia JM, van Driel TB, Castellano FN, Li X, Chen LX. Leshchev D, et al. Among authors: hsu dj. Angew Chem Int Ed Engl. 2023 Jul 10;62(28):e202304615. doi: 10.1002/anie.202304615. Epub 2023 May 31. Angew Chem Int Ed Engl. 2023. PMID: 37114904
The Role of Transient Intermediate Structures in the Unfolding of the Trp-Cage Fast-Folding Protein: Generating Ensembles from Time-Resolved X-ray Solution Scattering with Genetic Algorithms.
Chan AM, Nijhawan AK, Hsu DJ, Leshchev D, Rimmerman D, Kosheleva I, Kohlstedt KL, Chen LX. Chan AM, et al. Among authors: hsu dj. J Phys Chem Lett. 2023 Feb 9;14(5):1133-1139. doi: 10.1021/acs.jpclett.2c03680. Epub 2023 Jan 27. J Phys Chem Lett. 2023. PMID: 36705525 Free PMC article.
62 results