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NOX5-induced uncoupling of endothelial NO synthase is a causal mechanism and theragnostic target of an age-related hypertension endotype.
Elbatreek MH, Sadegh S, Anastasi E, Guney E, Nogales C, Kacprowski T, Hassan AA, Teubner A, Huang PH, Hsu CY, Schiffers PMH, Janssen GM, Kleikers PWM, Wipat A, Baumbach J, De Mey JGR, Schmidt HHHW. Elbatreek MH, et al. Among authors: hsu cy. PLoS Biol. 2020 Nov 10;18(11):e3000885. doi: 10.1371/journal.pbio.3000885. eCollection 2020 Nov. PLoS Biol. 2020. PMID: 33170835 Free PMC article.
Oxidative stress activates endothelial innate immunity via sterol regulatory element binding protein 2 (SREBP2) transactivation of microRNA-92a.
Chen Z, Wen L, Martin M, Hsu CY, Fang L, Lin FM, Lin TY, Geary MJ, Geary GG, Zhao Y, Johnson DA, Chen JW, Lin SJ, Chien S, Huang HD, Miller YI, Huang PH, Shyy JY. Chen Z, et al. Among authors: hsu cy. Circulation. 2015 Mar 3;131(9):805-14. doi: 10.1161/CIRCULATIONAHA.114.013675. Epub 2014 Dec 30. Circulation. 2015. PMID: 25550450 Free PMC article.
MicroRNA-92a Mediates Endothelial Dysfunction in CKD.
Shang F, Wang SC, Hsu CY, Miao Y, Martin M, Yin Y, Wu CC, Wang YT, Wu G, Chien S, Huang HD, Tarng DC, Shiu YT, Cheung AK, Huang PH, Chen Z, Shyy JY. Shang F, et al. Among authors: hsu cy. J Am Soc Nephrol. 2017 Nov;28(11):3251-3261. doi: 10.1681/ASN.2016111215. Epub 2017 Jul 10. J Am Soc Nephrol. 2017. PMID: 28696247 Free PMC article.
2,948 results