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HSP90 inhibitors induce GPNMB cell-surface expression by modulating lysosomal positioning and sensitize breast cancer cells to glembatumumab vedotin.
Biondini M, Kiepas A, El-Houjeiri L, Annis MG, Hsu BE, Fortier AM, Morin G, Martina JA, Sirois I, Aguilar-Mahecha A, Gruosso T, McGuirk S, Rose AAN, Tokat UM, Johnson RM, Sahin O, Bareke E, St-Pierre J, Park M, Basik M, Majewski J, Puertollano R, Pause A, Huang S, Keler T, Siegel PM. Biondini M, et al. Among authors: hsu be. Oncogene. 2022 Mar;41(12):1701-1717. doi: 10.1038/s41388-022-02206-z. Epub 2022 Feb 2. Oncogene. 2022. PMID: 35110681
p66ShcA functions as a contextual promoter of breast cancer metastasis.
Lewis K, Kiepas A, Hudson J, Senecal J, Ha JR, Voorand E, Annis MG, Sabourin V, Ahn R, La Selva R, Tabariès S, Hsu BE, Siegel MJ, Dankner M, Canedo EC, Lajoie M, Watson IR, Brown CM, Siegel PM, Ursini-Siegel J. Lewis K, et al. Among authors: hsu be. Breast Cancer Res. 2020 Jan 15;22(1):7. doi: 10.1186/s13058-020-1245-6. Breast Cancer Res. 2020. PMID: 31941526 Free PMC article.
Neutrophils: Orchestrators of the Malignant Phenotype.
Hsu BE, Shen Y, Siegel PM. Hsu BE, et al. Front Immunol. 2020 Aug 11;11:1778. doi: 10.3389/fimmu.2020.01778. eCollection 2020. Front Immunol. 2020. PMID: 32849639 Free PMC article. Review.
Translational control in the tumor microenvironment promotes lung metastasis: Phosphorylation of eIF4E in neutrophils.
Robichaud N, Hsu BE, Istomine R, Alvarez F, Blagih J, Ma EH, Morales SV, Dai DL, Li G, Souleimanova M, Guo Q, Del Rincon SV, Miller WH Jr, Ramón Y Cajal S, Park M, Jones RG, Piccirillo CA, Siegel PM, Sonenberg N. Robichaud N, et al. Among authors: hsu be. Proc Natl Acad Sci U S A. 2018 Mar 6;115(10):E2202-E2209. doi: 10.1073/pnas.1717439115. Epub 2018 Feb 20. Proc Natl Acad Sci U S A. 2018. PMID: 29463754 Free PMC article.
LKB1 deficiency in T cells promotes the development of gastrointestinal polyposis.
Poffenberger MC, Metcalfe-Roach A, Aguilar E, Chen J, Hsu BE, Wong AH, Johnson RM, Flynn B, Samborska B, Ma EH, Gravel SP, Tonelli L, Devorkin L, Kim P, Hall A, Izreig S, Loginicheva E, Beauchemin N, Siegel PM, Artyomov MN, Lum JJ, Zogopoulos G, Blagih J, Jones RG. Poffenberger MC, et al. Among authors: hsu be. Science. 2018 Jul 27;361(6400):406-411. doi: 10.1126/science.aan3975. Science. 2018. PMID: 30049881
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