Hsieh CJ - Search Results

1

PARP Theranostic Auger Emitters Are Cytotoxic in BRCA Mutant Ovarian Cancer and Viable Tumors from Ovarian Cancer Patients Enable Ex-Vivo Screening of Tumor Response.

Riad A, Gitto SB, Lee H, Winters HD, Martorano PM, Hsieh CJ, Xu K, Omran DK, Powell DJ Jr, Mach RH, Makvandi M. Riad A, et al. Among authors: hsieh cj. Molecules. 2020 Dec 19;25(24):6029. doi: 10.3390/molecules25246029. Molecules. 2020. PMID: 33352773 Free PMC article.

2

Development of a Positron Emission Tomography Radiotracer for Imaging Elevated Levels of Superoxide in Neuroinflammation.

Hou C, Hsieh CJ, Li S, Lee H, Graham TJ, Xu K, Weng CC, Doot RK, Chu W, Chakraborty SK, Dugan LL, Mintun MA, Mach RH. Hou C, et al. Among authors: hsieh cj. ACS Chem Neurosci. 2018 Mar 21;9(3):578-586. doi: 10.1021/acschemneuro.7b00385. Epub 2017 Dec 3. ACS Chem Neurosci. 2018. PMID: 29099578 Free PMC article.

3

A PET imaging agent for evaluating PARP-1 expression in ovarian cancer.

Makvandi M, Pantel A, Schwartz L, Schubert E, Xu K, Hsieh CJ, Hou C, Kim H, Weng CC, Winters H, Doot R, Farwell MD, Pryma DA, Greenberg RA, Mankoff DA, Simpkins F, Mach RH, Lin LL. Makvandi M, et al. Among authors: hsieh cj. J Clin Invest. 2018 May 1;128(5):2116-2126. doi: 10.1172/JCI97992. Epub 2018 Apr 16. J Clin Invest. 2018. PMID: 29509546 Free PMC article. Clinical Trial.

4

Alpha Synuclein Fibrils Contain Multiple Binding Sites for Small Molecules.

Hsieh CJ, Ferrie JJ, Xu K, Lee I, Graham TJA, Tu Z, Yu J, Dhavale D, Kotzbauer P, Petersson EJ, Mach RH. Hsieh CJ, et al. ACS Chem Neurosci. 2018 Nov 21;9(11):2521-2527. doi: 10.1021/acschemneuro.8b00177. Epub 2018 May 16. ACS Chem Neurosci. 2018. PMID: 29750499 Free PMC article.

5

Examination of Diazaspiro Cores as Piperazine Bioisosteres in the Olaparib Framework Shows Reduced DNA Damage and Cytotoxicity.

Reilly SW, Puentes LN, Wilson K, Hsieh CJ, Weng CC, Makvandi M, Mach RH. Reilly SW, et al. Among authors: hsieh cj. J Med Chem. 2018 Jun 28;61(12):5367-5379. doi: 10.1021/acs.jmedchem.8b00576. Epub 2018 Jun 14. J Med Chem. 2018. PMID: 29856625 Free PMC article.

6

Altering Nitrogen Heterocycles of AZD2461 Affords High Affinity Poly(ADP-ribose) Polymerase-1 Inhibitors with Decreased P-Glycoprotein Interactions.

Reilly SW, Puentes LN, Hsieh CJ, Makvandi M, Mach RH. Reilly SW, et al. Among authors: hsieh cj. ACS Omega. 2018 Aug 31;3(8):9997-10001. doi: 10.1021/acsomega.8b00896. Epub 2018 Aug 28. ACS Omega. 2018. PMID: 30198004 Free PMC article.

7

Chalcones and Five-Membered Heterocyclic Isosteres Bind to Alpha Synuclein Fibrils in Vitro.

Hsieh CJ, Xu K, Lee I, Graham TJA, Tu Z, Dhavale D, Kotzbauer P, Mach RH. Hsieh CJ, et al. ACS Omega. 2018 Apr 30;3(4):4486-4493. doi: 10.1021/acsomega.7b01897. Epub 2018 Apr 24. ACS Omega. 2018. PMID: 30221226 Free PMC article.

8

Validation of gallbladder absorbed radiation dose reduction simulation: human dosimetry of [¹⁸F]fluortriopride.

Doot RK, Dubroff JG, Scheuermann JS, Labban KJ, Cai J, Hsieh CJ, Li S, Lee H, Schubert EK, Hou C, Sheffer R, Schmitz A, Xu K, Mach RH. Doot RK, et al. Among authors: hsieh cj. EJNMMI Phys. 2018 Oct 8;5(1):21. doi: 10.1186/s40658-018-0219-6. EJNMMI Phys. 2018. PMID: 30294746 Free PMC article.

9

Synthesis and evaluation of an AZD2461 [¹⁸F]PET probe in non-human primates reveals the PARP-1 inhibitor to be non-blood-brain barrier penetrant.

Reilly SW, Puentes LN, Schmitz A, Hsieh CJ, Weng CC, Hou C, Li S, Kuo YM, Padakanti P, Lee H, Riad AA, Makvandi M, Mach RH. Reilly SW, et al. Among authors: hsieh cj. Bioorg Chem. 2019 Mar;83:242-249. doi: 10.1016/j.bioorg.2018.10.015. Epub 2018 Oct 17. Bioorg Chem. 2019. PMID: 30390553 Free PMC article.

10

Leveraging a Low-Affinity Diazaspiro Orthosteric Fragment to Reduce Dopamine D₃ Receptor (D₃R) Ligand Promiscuity across Highly Conserved Aminergic G-Protein-Coupled Receptors (GPCRs).

Reilly SW, Riad AA, Hsieh CJ, Sahlholm K, Jacome DA, Griffin S, Taylor M, Weng CC, Xu K, Kirschner N, Luedtke RR, Parry C, Malhotra S, Karanicolas J, Mach RH. Reilly SW, et al. Among authors: hsieh cj. J Med Chem. 2019 May 23;62(10):5132-5147. doi: 10.1021/acs.jmedchem.9b00412. Epub 2019 May 6. J Med Chem. 2019. PMID: 31021617

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

367 results

Search Page