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Investigation of the absolute bioavailability, mass balance, metabolism, and excretion of the cholesterol 24-hydroxylase inhibitor soticlestat in healthy volunteers.
Yin W, Ballard TE, Zhu SX, Hsiao S, Chen H, Li Y, Chowdhury SK, Stevenson A, Hui T, Hunt A, Asgharnejad M, Han S. Yin W, et al. Among authors: hsiao s. Br J Clin Pharmacol. 2024 Feb;90(2):516-527. doi: 10.1111/bcp.15917. Epub 2023 Nov 12. Br J Clin Pharmacol. 2024. PMID: 37771051 Clinical Trial.
A phase 2, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of soticlestat as adjunctive therapy in pediatric patients with Dravet syndrome or Lennox-Gastaut syndrome (ELEKTRA).
Hahn CD, Jiang Y, Villanueva V, Zolnowska M, Arkilo D, Hsiao S, Asgharnejad M, Dlugos D. Hahn CD, et al. Among authors: hsiao s. Epilepsia. 2022 Oct;63(10):2671-2683. doi: 10.1111/epi.17367. Epub 2022 Aug 4. Epilepsia. 2022. PMID: 35841234 Free PMC article. Clinical Trial.
Efficacy, safety, and tolerability of soticlestat as adjunctive therapy for the treatment of seizures in patients with Dup15q syndrome or CDKL5 deficiency disorder in an open-label signal-finding phase II study (ARCADE).
Demarest S, Jeste S, Agarwal N, Arkilo D, Asgharnejad M, Hsiao S, Thibert R. Demarest S, et al. Among authors: hsiao s. Epilepsy Behav. 2023 May;142:109173. doi: 10.1016/j.yebeh.2023.109173. Epub 2023 Apr 1. Epilepsy Behav. 2023. PMID: 37011526 Free article. Clinical Trial.
Real-world osimertinib pretreatment experience in patients with epidermal growth factor receptor T790M mutation-positive locally advanced or metastatic non-small cell lung cancer.
Chang GC, Shih JY, Yu CJ, Chao HS, Yang CT, Lin CC, Hung JY, Hsiao SY, Wang CC, Chian CF, Hsia TC, Chen YM. Chang GC, et al. Among authors: hsiao sy. PLoS One. 2024 May 16;19(5):e0303046. doi: 10.1371/journal.pone.0303046. eCollection 2024. PLoS One. 2024. PMID: 38753697 Free PMC article.
1,004 results