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Long-term administration of intravenous Trappsol® Cyclo™ (HP-β-CD) results in clinical benefits and stabilization or slowing of disease progression in patients with Niemann-Pick disease type C1: Results of an international 48-week Phase I/II trial.
Sharma R, Hastings C, Staretz-Chacham O, Raiman J, Paucar M, Spiegel R, Murray B, Hurst B, Liu B, Kjems L, Hrynkow S. Sharma R, et al. Among authors: hrynkow s. Mol Genet Metab Rep. 2023 Jun 29;36:100988. doi: 10.1016/j.ymgmr.2023.100988. eCollection 2023 Sep. Mol Genet Metab Rep. 2023. PMID: 37670901 Free PMC article.
Intravenous 2-hydroxypropyl-β-cyclodextrin (Trappsol® Cyclo™) demonstrates biological activity and impacts cholesterol metabolism in the central nervous system and peripheral tissues in adult subjects with Niemann-Pick Disease Type C1: Results of a phase 1 trial.
Hastings C, Liu B, Hurst B, Cox GF, Hrynkow S. Hastings C, et al. Among authors: hrynkow s. Mol Genet Metab. 2022 Dec;137(4):309-319. doi: 10.1016/j.ymgme.2022.10.004. Epub 2022 Oct 17. Mol Genet Metab. 2022. PMID: 36279795 Free article. Clinical Trial.
The Global Virus Network: Challenging chikungunya.
McSweegan E, Weaver SC, Lecuit M, Frieman M, Morrison TE, Hrynkow S. McSweegan E, et al. Among authors: hrynkow s. Antiviral Res. 2015 Aug;120:147-52. doi: 10.1016/j.antiviral.2015.06.003. Epub 2015 Jun 10. Antiviral Res. 2015. PMID: 26071007 Free PMC article. Review.
Merged cultures to empower women.
Jones KA, Malcom S, Hrynkow S. Jones KA, et al. Among authors: hrynkow s. Science. 2011 Apr 8;332(6026):149. doi: 10.1126/science.1206223. Science. 2011. PMID: 21474715 No abstract available.
Climate change and health research: time for teamwork.
Hrynkow SH. Hrynkow SH. Environ Health Perspect. 2008 Nov;116(11):A470. doi: 10.1289/ehp.12150. Environ Health Perspect. 2008. PMID: 19057678 Free PMC article. No abstract available.
Response to: "Rescuing the NIH before it is too late".
Alexander DF, Alving BM, Battey JF, Berg JM, Collins FS, Fauci AS, Gallin JI, Grady PA, Hodes RJ, Hrynkow SH, Insel TR, Jones JF, Katz SI, Landis SC, Li TK, Lindberg DA, Nabel EG, Niederhuber JE, Pettigrew RI, Rodgers GP, Ruffin J, Scarpa A, Schwartz DA, Sieving PA, Straus SE, Tabak LA, Volkow ND. Alexander DF, et al. Among authors: hrynkow sh. J Clin Invest. 2006 Jun;116(6):1462-3. doi: 10.1172/JCI28894. J Clin Invest. 2006. PMID: 16648877 Free PMC article.
Stigma and global health: looking forward.
Michels KM, Hofman KJ, Keusch GT, Hrynkow SH. Michels KM, et al. Among authors: hrynkow sh. Lancet. 2006 Feb 11;367(9509):538-9. doi: 10.1016/S0140-6736(06)68190-7. Lancet. 2006. PMID: 16473135 No abstract available.
15 results