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The PTPN2/PTPN1 inhibitor ABBV-CLS-484 unleashes potent anti-tumour immunity.
Baumgartner CK, Ebrahimi-Nik H, Iracheta-Vellve A, Hamel KM, Olander KE, Davis TGR, McGuire KA, Halvorsen GT, Avila OI, Patel CH, Kim SY, Kammula AV, Muscato AJ, Halliwill K, Geda P, Klinge KL, Xiong Z, Duggan R, Mu L, Yeary MD, Patti JC, Balon TM, Mathew R, Backus C, Kennedy DE, Chen A, Longenecker K, Klahn JT, Hrusch CL, Krishnan N, Hutchins CW, Dunning JP, Bulic M, Tiwari P, Colvin KJ, Chuong CL, Kohnle IC, Rees MG, Boghossian A, Ronan M, Roth JA, Wu MJ, Suermondt JSMT, Knudsen NH, Cheruiyot CK, Sen DR, Griffin GK, Golub TR, El-Bardeesy N, Decker JH, Yang Y, Guffroy M, Fossey S, Trusk P, Sun IM, Liu Y, Qiu W, Sun Q, Paddock MN, Farney EP, Matulenko MA, Beauregard C, Frost JM, Yates KB, Kym PR, Manguso RT. Baumgartner CK, et al. Among authors: hrusch cl. Nature. 2023 Oct;622(7984):850-862. doi: 10.1038/s41586-023-06575-7. Epub 2023 Oct 4. Nature. 2023. PMID: 37794185 Free PMC article.
Asthma-associated genetic variants induce IL33 differential expression through an enhancer-blocking regulatory region.
Aneas I, Decker DC, Howard CL, Sobreira DR, Sakabe NJ, Blaine KM, Stein MM, Hrusch CL, Montefiori LE, Tena J, Magnaye KM, Clay SM, Gern JE, Jackson DJ, Altman MC, Naureckas ET, Hogarth DK, White SR, Gomez-Skarmeta JL, Schoetler N, Ober C, Sperling AI, Nóbrega MA. Aneas I, et al. Among authors: hrusch cl. Nat Commun. 2021 Oct 21;12(1):6115. doi: 10.1038/s41467-021-26347-z. Nat Commun. 2021. PMID: 34675193 Free PMC article.
IL-33-mediated Eosinophilia Protects against Acute Lung Injury.
Krishack PA, Hollinger MK, Kuzel TG, Decker TS, Louviere TJ, Hrusch CL, Sperling AI, Verhoef PA. Krishack PA, et al. Among authors: hrusch cl. Am J Respir Cell Mol Biol. 2021 May;64(5):569-578. doi: 10.1165/rcmb.2020-0166OC. Am J Respir Cell Mol Biol. 2021. PMID: 33571420 Free PMC article.
Temperature Trajectory Subphenotypes Correlate With Immune Responses in Patients With Sepsis.
Bhavani SV, Wolfe KS, Hrusch CL, Greenberg JA, Krishack PA, Lin J, Lecompte-Osorio P, Carey KA, Kress JP, Coopersmith CM, Sperling AI, Verhoef PA, Churpek MM, Patel BK. Bhavani SV, et al. Among authors: hrusch cl. Crit Care Med. 2020 Nov;48(11):1645-1653. doi: 10.1097/CCM.0000000000004610. Crit Care Med. 2020. PMID: 32947475 Free PMC article.
22 results