Hristodorov D - Search Results

1

Granzyme M as a novel effector molecule for human cytolytic fusion proteins: CD64-specific cytotoxicity of Gm-H22(scFv) against leukemic cells.

Schiffer S, Letzian S, Jost E, Mladenov R, Hristodorov D, Huhn M, Fischer R, Barth S, Thepen T. Schiffer S, et al. Among authors: hristodorov d. Cancer Lett. 2013 Dec 1;341(2):178-85. doi: 10.1016/j.canlet.2013.08.005. Epub 2013 Aug 22. Cancer Lett. 2013. PMID: 23973499

2

Microtubule-associated protein tau facilitates the targeted killing of proliferating cancer cells in vitro and in a xenograft mouse tumour model in vivo.

Hristodorov D, Mladenov R, Pardo A, Pham AT, Huhn M, Fischer R, Thepen T, Barth S. Hristodorov D, et al. Br J Cancer. 2013 Sep 17;109(6):1570-8. doi: 10.1038/bjc.2013.457. Epub 2013 Aug 13. Br J Cancer. 2013. PMID: 23942071 Free PMC article.

3

Human microtubule-associated protein tau mediates targeted killing of CD30(+) lymphoma cells in vitro and inhibits tumour growth in vivo.

Hristodorov D, Nordlohne J, Mladenov R, Huhn M, Fischer R, Thepen T, Barth S. Hristodorov D, et al. Br J Haematol. 2014 Jan;164(2):251-7. doi: 10.1111/bjh.12626. Epub 2013 Oct 25. Br J Haematol. 2014. PMID: 24164493 Free article.

4

EpCAM-selective elimination of carcinoma cells by a novel MAP-based cytolytic fusion protein.

Hristodorov D, Amoury M, Mladenov R, Niesen J, Arens K, Berges N, Hein L, Di Fiore S, Pham AT, Huhn M, Helfrich W, Fischer R, Thepen T, Barth S. Hristodorov D, et al. Mol Cancer Ther. 2014 Sep;13(9):2194-202. doi: 10.1158/1535-7163.MCT-13-0781. Epub 2014 Jun 30. Mol Cancer Ther. 2014. PMID: 24980949

5

Recombinant H22(scFv) blocks CD64 and prevents the capture of anti-TNF monoclonal antibody. A potential strategy to enhance anti-TNF therapy.

Hristodorov D, Mladenov R, Brehm H, Fischer R, Barth S, Thepen T. Hristodorov D, et al. MAbs. 2014;6(5):1283-9. doi: 10.4161/mabs.32182. MAbs. 2014. PMID: 25517313 Free PMC article.

6

Targeted killing of rhabdomyosarcoma cells by a MAP-based human cytolytic fusion protein.

Brehm H, Hristodorov D, Pardo A, Mladenov R, Niesen J, Fischer R, Tur MK, Barth S. Brehm H, et al. Among authors: hristodorov d. Cancer Lett. 2015 Sep 1;365(2):149-55. doi: 10.1016/j.canlet.2015.04.004. Epub 2015 Apr 14. Cancer Lett. 2015. PMID: 25888452

7

The Fc-alpha receptor is a new target antigen for immunotherapy of myeloid leukemia.

Mladenov R, Hristodorov D, Cremer C, Hein L, Kreutzer F, Stroisch T, Niesen J, Brehm H, Blume T, Brümmendorf TH, Jost E, Thepen T, Fischer R, Stockmeyer B, Barth S, Stein C. Mladenov R, et al. Among authors: hristodorov d. Int J Cancer. 2015 Dec 1;137(11):2729-38. doi: 10.1002/ijc.29628. Epub 2015 Jun 12. Int J Cancer. 2015. PMID: 26041304 Free article.

8

Targeting CD64 mediates elimination of M1 but not M2 macrophages in vitro and in cutaneous inflammation in mice and patient biopsies.

Hristodorov D, Mladenov R, von Felbert V, Huhn M, Fischer R, Barth S, Thepen T. Hristodorov D, et al. MAbs. 2015;7(5):853-62. doi: 10.1080/19420862.2015.1066950. MAbs. 2015. PMID: 26218624 Free PMC article.

9

Fully human MAP-fusion protein selectively targets and eliminates proliferating CD64(+) M1 macrophages.

Hristodorov D, Mladenov R, Fischer R, Barth S, Thepen T. Hristodorov D, et al. Immunol Cell Biol. 2016 May;94(5):470-8. doi: 10.1038/icb.2016.4. Epub 2016 Jan 8. Immunol Cell Biol. 2016. PMID: 26743033

10

Granzyme B-based cytolytic fusion protein targeting EpCAM specifically kills triple negative breast cancer cells in vitro and inhibits tumor growth in a subcutaneous mouse tumor model.

Amoury M, Kolberg K, Pham AT, Hristodorov D, Mladenov R, Di Fiore S, Helfrich W, Kiessling F, Fischer R, Pardo A, Thepen T, Hussain AF, Nachreiner T, Barth S. Amoury M, et al. Among authors: hristodorov d. Cancer Lett. 2016 Mar 28;372(2):201-9. doi: 10.1016/j.canlet.2016.01.027. Epub 2016 Jan 21. Cancer Lett. 2016. PMID: 26806809

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