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The off-rate of monomers dissociating from amyloid-β protofibrils.
Grüning CS, Klinker S, Wolff M, Schneider M, Toksöz K, Klein AN, Nagel-Steger L, Willbold D, Hoyer W. Grüning CS, et al. Among authors: hoyer w. J Biol Chem. 2013 Dec 27;288(52):37104-11. doi: 10.1074/jbc.M113.513432. Epub 2013 Nov 18. J Biol Chem. 2013. PMID: 24247242 Free PMC article.
Sequestration of a β-hairpin for control of α-synuclein aggregation.
Mirecka EA, Shaykhalishahi H, Gauhar A, Akgül Ş, Lecher J, Willbold D, Stoldt M, Hoyer W. Mirecka EA, et al. Among authors: hoyer w. Angew Chem Int Ed Engl. 2014 Apr 14;53(16):4227-30. doi: 10.1002/anie.201309001. Epub 2014 Mar 12. Angew Chem Int Ed Engl. 2014. PMID: 24623599
Single fibril growth kinetics of α-synuclein.
Wördehoff MM, Bannach O, Shaykhalishahi H, Kulawik A, Schiefer S, Willbold D, Hoyer W, Birkmann E. Wördehoff MM, et al. Among authors: hoyer w. J Mol Biol. 2015 Mar 27;427(6 Pt B):1428-1435. doi: 10.1016/j.jmb.2015.01.020. Epub 2015 Feb 4. J Mol Biol. 2015. PMID: 25659910
QIAD assay for quantitating a compound's efficacy in elimination of toxic Aβ oligomers.
Brener O, Dunkelmann T, Gremer L, van Groen T, Mirecka EA, Kadish I, Willuweit A, Kutzsche J, Jürgens D, Rudolph S, Tusche M, Bongen P, Pietruszka J, Oesterhelt F, Langen KJ, Demuth HU, Janssen A, Hoyer W, Funke SA, Nagel-Steger L, Willbold D. Brener O, et al. Among authors: hoyer w. Sci Rep. 2015 Sep 23;5:13222. doi: 10.1038/srep13222. Sci Rep. 2015. PMID: 26394756 Free PMC article.
136 results