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Deacetylation of Fungal Exopolysaccharide Mediates Adhesion and Biofilm Formation.
Lee MJ, Geller AM, Bamford NC, Liu H, Gravelat FN, Snarr BD, Le Mauff F, Chabot J, Ralph B, Ostapska H, Lehoux M, Cerone RP, Baptista SD, Vinogradov E, Stajich JE, Filler SG, Howell PL, Sheppard DC. Lee MJ, et al. Among authors: howell pl. mBio. 2016 Apr 5;7(2):e00252-16. doi: 10.1128/mBio.00252-16. mBio. 2016. PMID: 27048799 Free PMC article.
Microbial glycoside hydrolases as antibiofilm agents with cross-kingdom activity.
Snarr BD, Baker P, Bamford NC, Sato Y, Liu H, Lehoux M, Gravelat FN, Ostapska H, Baistrocchi SR, Cerone RP, Filler EE, Parsek MR, Filler SG, Howell PL, Sheppard DC. Snarr BD, et al. Among authors: howell pl. Proc Natl Acad Sci U S A. 2017 Jul 3;114(27):7124-7129. doi: 10.1073/pnas.1702798114. Epub 2017 Jun 20. Proc Natl Acad Sci U S A. 2017. PMID: 28634301 Free PMC article.
PgaB orthologues contain a glycoside hydrolase domain that cleaves deacetylated poly-β(1,6)-N-acetylglucosamine and can disrupt bacterial biofilms.
Little DJ, Pfoh R, Le Mauff F, Bamford NC, Notte C, Baker P, Guragain M, Robinson H, Pier GB, Nitz M, Deora R, Sheppard DC, Howell PL. Little DJ, et al. Among authors: howell pl. PLoS Pathog. 2018 Apr 23;14(4):e1006998. doi: 10.1371/journal.ppat.1006998. eCollection 2018 Apr. PLoS Pathog. 2018. PMID: 29684093 Free PMC article.
Deacetylated microbial biofilm exopolysaccharides: It pays to be positive.
Ostapska H, Howell PL, Sheppard DC. Ostapska H, et al. Among authors: howell pl. PLoS Pathog. 2018 Dec 27;14(12):e1007411. doi: 10.1371/journal.ppat.1007411. eCollection 2018 Dec. PLoS Pathog. 2018. PMID: 30589915 Free PMC article. Review. No abstract available.
193 results