Howe EN - Search Results

1

CNS-Native Myeloid Cells Drive Immune Suppression in the Brain Metastatic Niche through Cxcl10.

Guldner IH, Wang Q, Yang L, Golomb SM, Zhao Z, Lopez JA, Brunory A, Howe EN, Zhang Y, Palakurthi B, Barron M, Gao H, Xuei X, Liu Y, Li J, Chen DZ, Landreth GE, Zhang S. Guldner IH, et al. Among authors: howe en. Cell. 2020 Nov 25;183(5):1234-1248.e25. doi: 10.1016/j.cell.2020.09.064. Epub 2020 Oct 27. Cell. 2020. PMID: 33113353 Free PMC article.

2

Tumor-induced Stromal STAT1 Accelerates Breast Cancer via Deregulating Tissue Homeostasis.

Zellmer VR, Schnepp PM, Fracci SL, Tan X, Howe EN, Zhang S. Zellmer VR, et al. Among authors: howe en. Mol Cancer Res. 2017 May;15(5):585-597. doi: 10.1158/1541-7786.MCR-16-0312. Epub 2017 Jan 20. Mol Cancer Res. 2017. PMID: 28108623 Free PMC article.

3

GAD1 Upregulation Programs Aggressive Features of Cancer Cell Metabolism in the Brain Metastatic Microenvironment.

Schnepp PM, Lee DD, Guldner IH, O'Tighearnaigh TK, Howe EN, Palakurthi B, Eckert KE, Toni TA, Ashfeld BL, Zhang S. Schnepp PM, et al. Among authors: howe en. Cancer Res. 2017 Jun 1;77(11):2844-2856. doi: 10.1158/0008-5472.CAN-16-2289. Epub 2017 Apr 11. Cancer Res. 2017. PMID: 28400476 Free PMC article.

4

Death effector domain-containing protein induces vulnerability to cell cycle inhibition in triple-negative breast cancer.

Ni Y, Schmidt KR, Werner BA, Koenig JK, Guldner IH, Schnepp PM, Tan X, Jiang L, Host M, Sun L, Howe EN, Wu J, Littlepage LE, Nakshatri H, Zhang S. Ni Y, et al. Among authors: howe en. Nat Commun. 2019 Jun 28;10(1):2860. doi: 10.1038/s41467-019-10743-7. Nat Commun. 2019. PMID: 31253784 Free PMC article.

5

Rab11b-mediated integrin recycling promotes brain metastatic adaptation and outgrowth.

Howe EN, Burnette MD, Justice ME, Schnepp PM, Hedrick V, Clancy JW, Guldner IH, Lamere AT, Li J, Aryal UK, D'Souza-Schorey C, Zartman JJ, Zhang S. Howe EN, et al. Nat Commun. 2020 Jun 15;11(1):3017. doi: 10.1038/s41467-020-16832-2. Nat Commun. 2020. PMID: 32541798 Free PMC article.

6

Aged Breast Extracellular Matrix Drives Mammary Epithelial Cells to an Invasive and Cancer-Like Phenotype.

Bahcecioglu G, Yue X, Howe E, Guldner I, Stack MS, Nakshatri H, Zhang S, Zorlutuna P. Bahcecioglu G, et al. Adv Sci (Weinh). 2021 Nov;8(22):e2100128. doi: 10.1002/advs.202100128. Epub 2021 Oct 7. Adv Sci (Weinh). 2021. PMID: 34617419 Free PMC article.

7

Targeting CXCL16 and STAT1 augments immune checkpoint blockade therapy in triple-negative breast cancer.

Palakurthi B, Fross SR, Guldner IH, Aleksandrovic E, Liu X, Martino AK, Wang Q, Neff RA, Golomb SM, Lewis C, Peng Y, Howe EN, Zhang S. Palakurthi B, et al. Among authors: howe en. Nat Commun. 2023 Apr 13;14(1):2109. doi: 10.1038/s41467-023-37727-y. Nat Commun. 2023. PMID: 37055410 Free PMC article.

8

Combined Scaffold Evaluation and Systems-Level Transcriptome-Based Analysis for Accelerated Lead Optimization Reveals Ribosomal Targeting Spirooxindole Cyclopropanes.

Rodriguez KX, Howe EN, Bacher EP, Burnette M, Meloche JL, Meisel J, Schnepp P, Tan X, Chang M, Zartman J, Zhang S, Ashfeld BL. Rodriguez KX, et al. Among authors: howe en. ChemMedChem. 2019 Sep 18;14(18):1653-1661. doi: 10.1002/cmdc.201900266. Epub 2019 Jul 1. ChemMedChem. 2019. PMID: 31140738 Free PMC article.

9

The miR-200 and miR-221/222 microRNA families: opposing effects on epithelial identity.

Howe EN, Cochrane DR, Richer JK. Howe EN, et al. J Mammary Gland Biol Neoplasia. 2012 Mar;17(1):65-77. doi: 10.1007/s10911-012-9244-6. Epub 2012 Feb 17. J Mammary Gland Biol Neoplasia. 2012. PMID: 22350980 Free PMC article. Review.

10

miR-200c targets a NF-κB up-regulated TrkB/NTF3 autocrine signaling loop to enhance anoikis sensitivity in triple negative breast cancer.

Howe EN, Cochrane DR, Cittelly DM, Richer JK. Howe EN, et al. PLoS One. 2012;7(11):e49987. doi: 10.1371/journal.pone.0049987. Epub 2012 Nov 21. PLoS One. 2012. PMID: 23185507 Free PMC article.

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