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Novel furano analogues of duocarmycin C1 and C2: design, synthesis, and biological evaluation of seco-iso-cyclopropylfurano[2,3-e]indoline (seco-iso-CFI) and seco-cyclopropyltetrahydrofurano[2,3-f]quinoline (seco-CFQ) analogues.
Bioorg Med Chem. 2002 Sep;10(9):2941-52. doi: 10.1016/s0968-0896(02)00157-8.
Bioorg Med Chem. 2002.
PMID: 12110316
A novel class of achiral seco-analogs of CC-1065 and the duocarmycins: design, synthesis, DNA binding, and anticancer properties.
Kupchinsky S, Centioni S, Howard T, Trzupek J, Roller S, Carnahan V, Townes H, Purnell B, Price C, Handl H, Summerville K, Johnson K, Toth J, Hudson S, Kiakos K, Hartley JA, Lee M.
Kupchinsky S, et al.
Bioorg Med Chem. 2004 Dec 1;12(23):6221-36. doi: 10.1016/j.bmc.2004.08.051.
Bioorg Med Chem. 2004.
PMID: 15519165
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Unexpected syntheses of seco-cyclopropyltetrahydroquinolines - from a radical 5-exo-trig cyclization reaction: analogs of CC-1065 and the duocarmycins.
Pati H, Howard T, Townes H, Lingerfelt B, McNulty L, Lee M.
Pati H, et al.
Molecules. 2004 Feb 28;9(3):125-33. doi: 10.3390/90300125.
Molecules. 2004.
PMID: 18007417
Free PMC article.
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Saccharomyces cerevisiae RAD5 influences the excision repair of DNA minor groove adducts.
Kiakos K, Howard TT, Lee M, Hartley JA, McHugh PJ.
Kiakos K, et al. Among authors: howard tt.
J Biol Chem. 2002 Nov 15;277(46):44576-81. doi: 10.1074/jbc.M208169200. Epub 2002 Sep 10.
J Biol Chem. 2002.
PMID: 12226100
Free article.
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Air-Filtering Masks for Respiratory Protection from PM2.5 and Pandemic Pathogens.
Xu J, Xiao X, Zhang W, Xu R, Kim SC, Cui Y, Howard TT, Wu E, Cui Y.
Xu J, et al. Among authors: howard tt.
One Earth. 2020 Nov 20;3(5):574-589. doi: 10.1016/j.oneear.2020.10.014.
One Earth. 2020.
PMID: 33748744
Free PMC article.
Review.
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