Howard MK - Search Results

1

Single administration vaccines: delivery challenges, in vivo performance, and translational considerations.

Michaelides K, Prasanna M, Badhan R, Mohammed AU, Walters A, Howard MK, Dulal P, Al-Khattawi A. Michaelides K, et al. Among authors: howard mk. Expert Rev Vaccines. 2023 Jan-Dec;22(1):579-595. doi: 10.1080/14760584.2023.2229431. Expert Rev Vaccines. 2023. PMID: 37395004 Free PMC article. Review.

2

Evaluation of the Delivery of a Live Attenuated Porcine Reproductive and Respiratory Syndrome Virus as a Unit Solid Dose Injectable Vaccine.

Hayhurst E, Rose E, Pedrera M, Edwards JC, Kotynska N, Grainger D, Sadigh Y, Flannery J, Bonnet L, Ritwik R, Dulal P, Howard MK, Graham SP. Hayhurst E, et al. Among authors: howard mk. Vaccines (Basel). 2022 Oct 30;10(11):1836. doi: 10.3390/vaccines10111836. Vaccines (Basel). 2022. PMID: 36366345 Free PMC article.

3

Molecular basis of proton-sensing by G protein-coupled receptors.

Howard MK, Hoppe N, Huang XP, Macdonald CB, Mehrota E, Grimes PR, Zahm A, Trinidad DD, English J, Coyote-Maestas W, Manglik A. Howard MK, et al. bioRxiv [Preprint]. 2024 Apr 18:2024.04.17.590000. doi: 10.1101/2024.04.17.590000. bioRxiv. 2024. PMID: 38659943 Free PMC article. Preprint.

4

Profiling the proximal proteome of the activated μ-opioid receptor.

Polacco BJ, Lobingier BT, Blythe EE, Abreu N, Khare P, Howard MK, Gonzalez-Hernandez AJ, Xu J, Li Q, Novy B, Naing ZZC, Shoichet BK, Coyote-Maestas W, Levitz J, Krogan NJ, Von Zastrow M, Hüttenhain R. Polacco BJ, et al. Among authors: howard mk. Nat Chem Biol. 2024 Mar 25. doi: 10.1038/s41589-024-01588-3. Online ahead of print. Nat Chem Biol. 2024. PMID: 38528119

5

HTRA1 disaggregates α-synuclein amyloid fibrils and converts them into non-toxic and seeding incompetent species.

Chen S, Puri A, Bell B, Fritsche J, Palacios HH, Balch M, Sprunger ML, Howard MK, Ryan JJ, Haines JN, Patti GJ, Davis AA, Jackrel ME. Chen S, et al. Among authors: howard mk. Nat Commun. 2024 Mar 18;15(1):2436. doi: 10.1038/s41467-024-46538-8. Nat Commun. 2024. PMID: 38499535 Free PMC article.

6

Amyloidogenic propensity of self-assembling peptides and their adjuvant potential for use as DNA vaccines.

Shrimali PC, Chen S, Das A, Dreher R, Howard MK, Ryan JJ, Buck J, Kim D, Sprunger ML, Rudra JS, Jackrel ME. Shrimali PC, et al. Among authors: howard mk. Acta Biomater. 2023 Oct 1;169:464-476. doi: 10.1016/j.actbio.2023.08.015. Epub 2023 Aug 14. Acta Biomater. 2023. PMID: 37586449 Free article.

7

Probing the drivers of Staphylococcus aureus biofilm protein amyloidogenesis and disrupting biofilms with engineered protein disaggregases.

Howard MK, Miller KR, Sohn BS, Ryan JJ, Xu A, Jackrel ME. Howard MK, et al. mBio. 2023 Aug 31;14(4):e0058723. doi: 10.1128/mbio.00587-23. Epub 2023 May 17. mBio. 2023. PMID: 37195208 Free PMC article.

8

Functional analysis of proposed substrate-binding residues of Hsp104.

Howard MK, Sohn BS, von Borcke J, Xu A, Jackrel ME. Howard MK, et al. PLoS One. 2020 Mar 10;15(3):e0230198. doi: 10.1371/journal.pone.0230198. eCollection 2020. PLoS One. 2020. PMID: 32155221 Free PMC article.

9

Molecular Basis of the Divergent Immunogenicity of Two Pediatric Tick-Borne Encephalitis Virus Vaccines.

Beck Y, Fritz R, Orlinger K, Kiermayr S, Ilk R, Portsmouth D, Pöllabauer EM, Löw-Baselli A, Hessel A, Kölch D, Howard MK, Barrett PN, Kreil TR. Beck Y, et al. Among authors: howard mk. J Virol. 2015 Dec 9;90(4):1964-72. doi: 10.1128/JVI.02985-15. Print 2016 Feb 15. J Virol. 2015. PMID: 26656681 Free PMC article. Clinical Trial.

10

Dyslipidemia and its association with meibomian gland dysfunction.

Braich PS, Howard MK, Singh JS. Braich PS, et al. Among authors: howard mk. Int Ophthalmol. 2016 Aug;36(4):469-76. doi: 10.1007/s10792-015-0149-4. Epub 2015 Oct 29. Int Ophthalmol. 2016. PMID: 26515235

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