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Synthesis and Evaluation of Antimicrobial Activity and Molecular Dock - ing of New N-1,3-thiazol-2-ylacetamides of Condensed Pyrido[3',2':4,5] furo(thieno)[3,2-d]pyrimidines.
Sirakanyan SN, Kartsev VG, Geronikaki A, Spinelli D, Petrou A, Hakobyan EK, Glamoclija J, Ivanov M, Sokovic M, Hovakimyan AA. Sirakanyan SN, et al. Among authors: hovakimyan aa. Curr Top Med Chem. 2020;20(24):2192-2209. doi: 10.2174/1568026620666200628145308. Curr Top Med Chem. 2020. PMID: 32598259
A new microtubule-stabilizing agent shows potent antiviral effects against African swine fever virus with no cytotoxicity.
Sirakanyan S, Arabyan E, Hakobyan A, Hakobyan T, Chilingaryan G, Sahakyan H, Sargsyan A, Arakelov G, Nazaryan K, Izmailyan R, Abroyan L, Karalyan Z, Arakelova E, Hakobyan E, Hovakimyan A, Serobian A, Neves M, Ferreira J, Ferreira F, Zakaryan H. Sirakanyan S, et al. Emerg Microbes Infect. 2021 Dec;10(1):783-796. doi: 10.1080/22221751.2021.1902751. Emerg Microbes Infect. 2021. PMID: 33706677 Free PMC article.
Synthesis and Neurotropic Activity of New Heterocyclic Systems: Pyridofuro[3,2-d]pyrrolo[1,2-a]pyrimidines, Pyridofuro[3,2-d]pyrido[1,2-a]pyrimidines and Pyridofuro[3',2':4,5]pyrimido[1,2-a]azepines.
Sirakanyan SN, Spinelli D, Geronikaki A, Kartsev V, Hakobyan EK, Petrou A, Paronikyan RG, Nazaryan IM, Akopyan HH, Hovakimyan AA. Sirakanyan SN, et al. Among authors: hovakimyan aa. Molecules. 2021 Jun 1;26(11):3320. doi: 10.3390/molecules26113320. Molecules. 2021. PMID: 34205930 Free PMC article.
New Bicyclic Pyridine-Based Hybrids Linked to the 1,2,3-Triazole Unit: Synthesis via Click Reaction and Evaluation of Neurotropic Activity and Molecular Docking.
Sirakanyan SN, Spinelli D, Petrou A, Geronikaki A, Kartsev VG, Hakobyan EK, Yegoryan HA, Zuppiroli L, Zuppiroli R, Ayvazyan AG, Paronikyan RG, Arakelyan TA, Hovakimyan AA. Sirakanyan SN, et al. Among authors: hovakimyan aa. Molecules. 2023 Jan 17;28(3):921. doi: 10.3390/molecules28030921. Molecules. 2023. PMID: 36770592 Free PMC article.
In silico Design, Synthesis and Biological Evaluation of Novel Thieno[3,2-d]pyrimidine Derivatives for Cancer Therapy - A Preliminary Study on the Inhibitory Potential towards ATR Kinase Domain and PIKK Family.
Sirakanyan SN, Dilip H, Geronikaki A, Spinelli D, Kirubakaran S, Petrou A, Hakobyan EK, Kartsev VG, Paronikyan EG, Yegoryan HA, Yermalovyan LV, Hovakimyan AA. Sirakanyan SN, et al. Among authors: hovakimyan aa. Chem Biodivers. 2024 Mar;21(3):e202302071. doi: 10.1002/cbdv.202302071. Epub 2024 Feb 16. Chem Biodivers. 2024. PMID: 38230843