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Selective blockade of the hydrolysis of the endocannabinoid 2-arachidonoylglycerol impairs learning and memory performance while producing antinociceptive activity in rodents.
Sci Rep. 2015 Jan 6;5:7642. doi: 10.1038/srep07642.
Sci Rep. 2015.
PMID: 25560837
Free PMC article.
Structural basis for human monoglyceride lipase inhibition.
Bertrand T, Augé F, Houtmann J, Rak A, Vallée F, Mikol V, Berne PF, Michot N, Cheuret D, Hoornaert C, Mathieu M.
Bertrand T, et al. Among authors: houtmann j.
J Mol Biol. 2010 Feb 26;396(3):663-73. doi: 10.1016/j.jmb.2009.11.060. Epub 2009 Dec 3.
J Mol Biol. 2010.
PMID: 19962385
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Discovery and Pharmacokinetic and Pharmacological Properties of the Potent and Selective MET Kinase Inhibitor 1-{6-[6-(4-Fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-3-ylsulfanyl]benzothiazol-2-yl}-3-(2-morpholin-4-ylethyl)urea (SAR125844).
Ugolini A, Kenigsberg M, Rak A, Vallée F, Houtmann J, Lowinski M, Capdevila C, Khider J, Albert E, Martinet N, Nemecek C, Grapinet S, Bacqué E, Roesner M, Delaisi C, Calvet L, Bonche F, Semiond D, Egile C, Goulaouic H, Schio L.
Ugolini A, et al. Among authors: houtmann j.
J Med Chem. 2016 Aug 11;59(15):7066-74. doi: 10.1021/acs.jmedchem.6b00280. Epub 2016 Jul 13.
J Med Chem. 2016.
PMID: 27355974
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KRAS G12C fragment screening renders new binding pockets.
Mathieu M, Steier V, Fassy F, Delorme C, Papin D, Genet B, Duffieux F, Bertrand T, Delarbre L, Le-Borgne H, Parent A, Didier P, Marquette JP, Lowinski M, Houtmann J, Lamberton A, Debussche L, Alexey R.
Mathieu M, et al. Among authors: houtmann j.
Small GTPases. 2022 Jan;13(1):225-238. doi: 10.1080/21541248.2021.1979360. Epub 2021 Sep 24.
Small GTPases. 2022.
PMID: 34558391
Free PMC article.
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Peliosis hepatis and sinusoidal dilation during infection by the human immunodeficiency virus (HIV). An ultrastructural study.
Scoazec JY, Marche C, Girard PM, Houtmann J, Durand-Schneider AM, Saimot AG, Benhamou JP, Feldmann G.
Scoazec JY, et al. Among authors: houtmann j.
Am J Pathol. 1988 Apr;131(1):38-47.
Am J Pathol. 1988.
PMID: 3354642
Free PMC article.
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