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Selective Modulation of the Human Glucocorticoid Receptor Compromises GR Chromatin Occupancy and Recruitment of p300/CBP and the Mediator Complex.
Van Moortel L, Verhee A, Thommis J, Houtman R, Melchers D, Delhaye L, Van Leene C, Hellemans M, Gevaert K, Eyckerman S, De Bosscher K. Van Moortel L, et al. Among authors: houtman r. Mol Cell Proteomics. 2024 Mar;23(3):100741. doi: 10.1016/j.mcpro.2024.100741. Epub 2024 Feb 20. Mol Cell Proteomics. 2024. PMID: 38387774 Free PMC article.
Optimizing the implementation of a forest fuel break network.
Ager AA, Day MA, Aparício BA, Houtman R, Stinchfield A. Ager AA, et al. Among authors: houtman r. PLoS One. 2023 Dec 13;18(12):e0295392. doi: 10.1371/journal.pone.0295392. eCollection 2023. PLoS One. 2023. PMID: 38091301 Free PMC article.
A phospholipid mimetic targeting LRH-1 ameliorates colitis.
Mays SG, D'Agostino EH, Flynn AR, Huang X, Wang G, Liu X, Millings EJ, Okafor CD, Patel A, Cato ML, Cornelison JL, Melchers D, Houtman R, Moore DD, Calvert JW, Jui NT, Ortlund EA. Mays SG, et al. Among authors: houtman r. Cell Chem Biol. 2022 Jul 21;29(7):1174-1186.e7. doi: 10.1016/j.chembiol.2022.03.001. Epub 2022 Mar 21. Cell Chem Biol. 2022. PMID: 35316658 Free article.
Profile of estetrol, a promising native estrogen for oral contraception and the relief of climacteric symptoms of menopause.
Gérard C, Arnal JF, Jost M, Douxfils J, Lenfant F, Fontaine C, Houtman R, Archer DF, Reid RL, Lobo RA, Gaspard U, Coelingh Bennink HJT, Creinin MD, Foidart JM. Gérard C, et al. Among authors: houtman r. Expert Rev Clin Pharmacol. 2022 Feb;15(2):121-137. doi: 10.1080/17512433.2022.2054413. Epub 2022 Mar 27. Expert Rev Clin Pharmacol. 2022. PMID: 35306927 Review.
Dual-mechanism estrogen receptor inhibitors.
Min J, Nwachukwu JC, Min CK, Njeri JW, Srinivasan S, Rangarajan ES, Nettles CC, Sanabria Guillen V, Ziegler Y, Yan S, Carlson KE, Hou Y, Kim SH, Novick S, Pascal BD, Houtman R, Griffin PR, Izard T, Katzenellenbogen BS, Katzenellenbogen JA, Nettles KW. Min J, et al. Among authors: houtman r. Proc Natl Acad Sci U S A. 2021 Aug 31;118(35):e2101657118. doi: 10.1073/pnas.2101657118. Proc Natl Acad Sci U S A. 2021. PMID: 34452998 Free PMC article.
Carbonyl reductase 1 amplifies glucocorticoid action in adipose tissue and impairs glucose tolerance in lean mice.
Bell RMB, Villalobos E, Nixon M, Miguelez-Crespo A, Murphy L, Fawkes A, Coutts A, Sharp MGF, Koerner MV, Allan E, Meijer OC, Houtman R, Odermatt A, Beck KR, Denham SG, Lee P, Homer NZM, Walker BR, Morgan RA. Bell RMB, et al. Among authors: houtman r. Mol Metab. 2021 Jun;48:101225. doi: 10.1016/j.molmet.2021.101225. Epub 2021 Mar 27. Mol Metab. 2021. PMID: 33785425 Free PMC article.
Chemical systems biology reveals mechanisms of glucocorticoid receptor signaling.
Bruno NE, Nwachukwu JC, Srinivasan S, Nettles CC, Izard T, Jin Z, Nowak J, Cameron MD, Boregowda SV, Phinney DG, Elemento O, Liu X, Ortlund EA, Houtman R, Stavreva DA, Hager GL, Kamenecka TM, Kojetin DJ, Nettles KW. Bruno NE, et al. Among authors: houtman r. Nat Chem Biol. 2021 Mar;17(3):307-316. doi: 10.1038/s41589-020-00719-w. Epub 2021 Jan 28. Nat Chem Biol. 2021. PMID: 33510451 Free PMC article.
70 results