Houtman R - Search Results

1

Selective Mineralocorticoid Receptor Cofactor Modulation as Molecular Basis for Finerenone's Antifibrotic Activity.

Grune J, Beyhoff N, Smeir E, Chudek R, Blumrich A, Ban Z, Brix S, Betz IR, Schupp M, Foryst-Ludwig A, Klopfleisch R, Stawowy P, Houtman R, Kolkhof P, Kintscher U. Grune J, et al. Among authors: houtman r. Hypertension. 2018 Apr;71(4):599-608. doi: 10.1161/HYPERTENSIONAHA.117.10360. Epub 2018 Feb 5. Hypertension. 2018. PMID: 29437893

2

The effects of all-trans retinoic acid on estrogen receptor signaling in the estrogen-sensitive MCF/BUS subline.

Miro Estruch I, de Haan LHJ, Melchers D, Houtman R, Louisse J, Groten JP, Rietjens IMCM. Miro Estruch I, et al. Among authors: houtman r. J Recept Signal Transduct Res. 2018 Apr;38(2):112-121. doi: 10.1080/10799893.2018.1436559. Epub 2018 Feb 15. J Recept Signal Transduct Res. 2018. PMID: 29447503

3

A Mixed Glucocorticoid/Mineralocorticoid Selective Modulator With Dominant Antagonism in the Male Rat Brain.

Atucha E, Zalachoras I, van den Heuvel JK, van Weert LT, Melchers D, Mol IM, Belanoff JK, Houtman R, Hunt H, Roozendaal B, Meijer OC. Atucha E, et al. Among authors: houtman r. Endocrinology. 2015 Nov;156(11):4105-14. doi: 10.1210/en.2015-1390. Epub 2015 Aug 25. Endocrinology. 2015. PMID: 26305887

4

The selective glucocorticoid receptor antagonist CORT125281 has tissue-specific activity.

Koorneef LL, Kroon J, Viho EMG, Wahl LF, Heckmans KML, van Dorst MMAR, Hoekstra M, Houtman R, Hunt H, Meijer OC. Koorneef LL, et al. Among authors: houtman r. J Endocrinol. 2020 Jul;246(1):79-92. doi: 10.1530/JOE-19-0486. J Endocrinol. 2020. PMID: 32369774 Free PMC article.

5

The Nuclear Receptor PPARγ Controls Progressive Macrophage Polarization as a Ligand-Insensitive Epigenomic Ratchet of Transcriptional Memory.

Daniel B, Nagy G, Czimmerer Z, Horvath A, Hammers DW, Cuaranta-Monroy I, Poliska S, Tzerpos P, Kolostyak Z, Hays TT, Patsalos A, Houtman R, Sauer S, Francois-Deleuze J, Rastinejad F, Balint BL, Sweeney HL, Nagy L. Daniel B, et al. Among authors: houtman r. Immunity. 2018 Oct 16;49(4):615-626.e6. doi: 10.1016/j.immuni.2018.09.005. Immunity. 2018. PMID: 30332629 Free PMC article.

6

Compound A influences gene regulation of the Dexamethasone-activated glucocorticoid receptor by alternative cofactor recruitment.

Desmet SJ, Bougarne N, Van Moortel L, De Cauwer L, Thommis J, Vuylsteke M, Ratman D, Houtman R, Tavernier J, De Bosscher K. Desmet SJ, et al. Among authors: houtman r. Sci Rep. 2017 Aug 14;7(1):8063. doi: 10.1038/s41598-017-07941-y. Sci Rep. 2017. PMID: 28808239 Free PMC article.

7

Identification of coregulators influenced by estrogen receptor subtype specific binding of the ER antagonists 4-hydroxytamoxifen and fulvestrant.

Evers NM, Wang S, van den Berg JH, Houtman R, Melchers D, de Haan LH, Ederveen AG, Groten JP, Rietjens IM. Evers NM, et al. Among authors: houtman r. Chem Biol Interact. 2014 Sep 5;220:222-30. doi: 10.1016/j.cbi.2014.06.019. Epub 2014 Jul 8. Chem Biol Interact. 2014. PMID: 25014417

8

Profiling of 3696 Nuclear Receptor-Coregulator Interactions: A Resource for Biological and Clinical Discovery.

Broekema MF, Hollman DAA, Koppen A, van den Ham HJ, Melchers D, Pijnenburg D, Ruijtenbeek R, van Mil SWC, Houtman R, Kalkhoven E. Broekema MF, et al. Among authors: houtman r. Endocrinology. 2018 Jun 1;159(6):2397-2407. doi: 10.1210/en.2018-00149. Endocrinology. 2018. PMID: 29718163

9

Corticosteroid Action in the Brain: The Potential of Selective Receptor Modulation.

Viho EMG, Buurstede JC, Mahfouz A, Koorneef LL, van Weert LTCM, Houtman R, Hunt HJ, Kroon J, Meijer OC. Viho EMG, et al. Among authors: houtman r. Neuroendocrinology. 2019;109(3):266-276. doi: 10.1159/000499659. Epub 2019 Mar 19. Neuroendocrinology. 2019. PMID: 30884490 Free PMC article. Review.

10

Carbonyl reductase 1 amplifies glucocorticoid action in adipose tissue and impairs glucose tolerance in lean mice.

Bell RMB, Villalobos E, Nixon M, Miguelez-Crespo A, Murphy L, Fawkes A, Coutts A, Sharp MGF, Koerner MV, Allan E, Meijer OC, Houtman R, Odermatt A, Beck KR, Denham SG, Lee P, Homer NZM, Walker BR, Morgan RA. Bell RMB, et al. Among authors: houtman r. Mol Metab. 2021 Jun;48:101225. doi: 10.1016/j.molmet.2021.101225. Epub 2021 Mar 27. Mol Metab. 2021. PMID: 33785425 Free PMC article.

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