Houston SD - Search Results

1

Cage hydrocarbons as linkers in dimeric drug design: Case studies with trimethoprim and tedizolid.

Vujcic B, Wyllie J, Tania, Burns J, White KF, Cromwell S, Lupton DW, Dutton JL, Soares da Costa TP, Houston SD. Vujcic B, et al. Among authors: houston sd. Bioorg Med Chem Lett. 2023 Jan 15;80:129086. doi: 10.1016/j.bmcl.2022.129086. Epub 2022 Nov 21. Bioorg Med Chem Lett. 2023. PMID: 36423825

2

PhI(OTf)₂ Does Not Exist (Yet)*.

Tania, Houston SD, Sharp-Bucknall L, Poynder TB, Albayer M, Dutton JL. Tania, et al. Among authors: houston sd. Chemistry. 2020 Dec 4;26(68):15863-15866. doi: 10.1002/chem.202003819. Epub 2020 Oct 29. Chemistry. 2020. PMID: 32959910

3

PhICl₂ is activated by chloride ions.

Tania, Poynder TB, Kaur A, Barwise L, Houston SD, Nair AJ, Clegg JK, Wilson DJD, Dutton JL. Tania, et al. Among authors: houston sd. Dalton Trans. 2021 Aug 11. doi: 10.1039/d1dt02565a. Online ahead of print. Dalton Trans. 2021. PMID: 34378593

4

Determining the necessity of phenyl ring π-character in warfarin.

Xing H, Houston SD, Chen X, Jin DY, Savage GP, Tie JK, Williams CM. Xing H, et al. Among authors: houston sd. Bioorg Med Chem Lett. 2019 Aug 1;29(15):1954-1956. doi: 10.1016/j.bmcl.2019.05.039. Epub 2019 May 23. Bioorg Med Chem Lett. 2019. PMID: 31147103 Free PMC article.

5

The cubane paradigm in bioactive molecule discovery: further scope, limitations and the cyclooctatetraene complement.

Houston SD, Fahrenhorst-Jones T, Xing H, Chalmers BA, Sykes ML, Stok JE, Farfan Soto C, Burns JM, Bernhardt PV, De Voss JJ, Boyle GM, Smith MT, Tsanaktsidis J, Savage GP, Avery VM, Williams CM. Houston SD, et al. Org Biomol Chem. 2019 Jul 17;17(28):6790-6798. doi: 10.1039/c9ob01238a. Org Biomol Chem. 2019. PMID: 31241113

6

Nonclassical Phenyl Bioisosteres as Effective Replacements in a Series of Novel Open-Source Antimalarials.

Tse EG, Houston SD, Williams CM, Savage GP, Rendina LM, Hallyburton I, Anderson M, Sharma R, Walker GS, Obach RS, Todd MH. Tse EG, et al. Among authors: houston sd. J Med Chem. 2020 Oct 22;63(20):11585-11601. doi: 10.1021/acs.jmedchem.0c00746. Epub 2020 Sep 30. J Med Chem. 2020. PMID: 32678591

7

Cyclooctatetraene: A Bioactive Cubane Paradigm Complement.

Xing H, Houston SD, Chen X, Ghassabian S, Fahrenhorst-Jones T, Kuo A, Murray CP, Conn KA, Jaeschke KN, Jin DY, Pasay C, Bernhardt PV, Burns JM, Tsanaktsidis J, Savage GP, Boyle GM, De Voss JJ, McCarthy J, Walter GH, Burne THJ, Smith MT, Tie JK, Williams CM. Xing H, et al. Among authors: houston sd. Chemistry. 2019 Feb 21;25(11):2729-2734. doi: 10.1002/chem.201806277. Epub 2019 Jan 25. Chemistry. 2019. PMID: 30681236 Free PMC article.

8

Cubane, Bicyclo[1.1.1]pentane and Bicyclo[2.2.2]octane: Impact and Thermal Sensitiveness of Carboxyl-, Hydroxymethyl- and Iodo-substituents.

Dallaston MA, Houston SD, Williams CM. Dallaston MA, et al. Among authors: houston sd. Chemistry. 2020 Sep 16;26(52):11966-11970. doi: 10.1002/chem.202001658. Epub 2020 Aug 20. Chemistry. 2020. PMID: 32820575

9

Enantioselective synthesis of (R)-2-cubylglycine including unprecedented rhodium mediated C-H insertion of cubane.

Houston SD, Chalmers BA, Savage GP, Williams CM. Houston SD, et al. Org Biomol Chem. 2019 Jan 31;17(5):1067-1070. doi: 10.1039/c8ob02959h. Org Biomol Chem. 2019. PMID: 30644962

10

Cyclooctatetraenes through Valence Isomerization of Cubanes: Scope and Limitations.

Houston SD, Xing H, Bernhardt PV, Vanden Berg TJ, Tsanaktsidis J, Savage GP, Williams CM. Houston SD, et al. Chemistry. 2019 Feb 21;25(11):2735-2739. doi: 10.1002/chem.201805124. Epub 2019 Jan 29. Chemistry. 2019. PMID: 30693963

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