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Page 1
Profiling of Copy Number Alterations Using Low-Coverage Whole-Genome Sequencing Informs Differential Diagnosis and Prognosis in Primary Cutaneous Follicle Center Lymphoma.
Bátai B, Kiss L, Varga L, Nagy Á, Househam J, Baker AM, László T, Udvari A, Horváth R, Nagy T, Csomor J, Szakonyi J, Schneider T, Graham TA, Alpár D, Fitzgibbon J, Szepesi Á, Bödör C. Bátai B, et al. Among authors: househam j. Mod Pathol. 2024 Mar 7;37(5):100465. doi: 10.1016/j.modpat.2024.100465. Online ahead of print. Mod Pathol. 2024. PMID: 38460675 Free article.
Epigenome and early selection determine the tumour-immune evolutionary trajectory of colorectal cancer.
Lakatos E, Gunasri V, Zapata L, Househam J, Heide T, Trahearn N, Swinyard O, Cisneros L, Lynn C, Mossner M, Kimberley C, Spiteri I, Cresswell GD, Llibre-Palomar G, Mitchison M, Maley CC, Jansen M, Rodriguez-Justo M, Bridgewater J, Baker AM, Sottoriva A, Graham TA. Lakatos E, et al. Among authors: househam j. bioRxiv [Preprint]. 2024 Feb 14:2024.02.12.579956. doi: 10.1101/2024.02.12.579956. bioRxiv. 2024. PMID: 38405882 Free PMC article. Preprint.
Phenotypic noise and plasticity in cancer evolution.
Whiting FJH, Househam J, Baker AM, Sottoriva A, Graham TA. Whiting FJH, et al. Among authors: househam j. Trends Cell Biol. 2023 Nov 13:S0962-8924(23)00206-4. doi: 10.1016/j.tcb.2023.10.002. Online ahead of print. Trends Cell Biol. 2023. PMID: 37968225 Free article. Review.
Evolutionary and immune microenvironment dynamics during neoadjuvant treatment of oesophagael adenocarcinoma.
Barroux M, Househam J, Lakatos E, Ronel T, Baker AM, Salié H, Mossner M, Smith K, Kimberley C, Nowinski S, Berner A, Gunasri V, Jansen M, Caravagna G, Steiger K, Slotta-Huspenina J, Weichert W, Alberstmeier M, Chain B, Friess H, Bengsch B, Schmid R, Siveke J, Quante M, Graham T. Barroux M, et al. Among authors: househam j. Res Sq [Preprint]. 2023 Apr 13:rs.3.rs-2738048. doi: 10.21203/rs.3.rs-2738048/v1. Res Sq. 2023. PMID: 37090678 Free PMC article. Preprint.
Phenotypic plasticity and genetic control in colorectal cancer evolution.
Househam J, Heide T, Cresswell GD, Spiteri I, Kimberley C, Zapata L, Lynn C, James C, Mossner M, Fernandez-Mateos J, Vinceti A, Baker AM, Gabbutt C, Berner A, Schmidt M, Chen B, Lakatos E, Gunasri V, Nichol D, Costa H, Mitchinson M, Ramazzotti D, Werner B, Iorio F, Jansen M, Caravagna G, Barnes CP, Shibata D, Bridgewater J, Rodriguez-Justo M, Magnani L, Sottoriva A, Graham TA. Househam J, et al. Nature. 2022 Nov;611(7937):744-753. doi: 10.1038/s41586-022-05311-x. Epub 2022 Oct 26. Nature. 2022. PMID: 36289336 Free PMC article.
The co-evolution of the genome and epigenome in colorectal cancer.
Heide T, Househam J, Cresswell GD, Spiteri I, Lynn C, Mossner M, Kimberley C, Fernandez-Mateos J, Chen B, Zapata L, James C, Barozzi I, Chkhaidze K, Nichol D, Gunasri V, Berner A, Schmidt M, Lakatos E, Baker AM, Costa H, Mitchinson M, Piazza R, Jansen M, Caravagna G, Ramazzotti D, Shibata D, Bridgewater J, Rodriguez-Justo M, Magnani L, Graham TA, Sottoriva A. Heide T, et al. Among authors: househam j. Nature. 2022 Nov;611(7937):733-743. doi: 10.1038/s41586-022-05202-1. Epub 2022 Oct 26. Nature. 2022. PMID: 36289335 Free PMC article.
Fluctuating methylation clocks for cell lineage tracing at high temporal resolution in human tissues.
Gabbutt C, Schenck RO, Weisenberger DJ, Kimberley C, Berner A, Househam J, Lakatos E, Robertson-Tessi M, Martin I, Patel R, Clark SK, Latchford A, Barnes CP, Leedham SJ, Anderson ARA, Graham TA, Shibata D. Gabbutt C, et al. Among authors: househam j. Nat Biotechnol. 2022 May;40(5):720-730. doi: 10.1038/s41587-021-01109-w. Epub 2022 Jan 3. Nat Biotechnol. 2022. PMID: 34980912 Free PMC article.
Evolutionary dynamics of neoantigens in growing tumors.
Lakatos E, Williams MJ, Schenck RO, Cross WCH, Househam J, Zapata L, Werner B, Gatenbee C, Robertson-Tessi M, Barnes CP, Anderson ARA, Sottoriva A, Graham TA. Lakatos E, et al. Among authors: househam j. Nat Genet. 2020 Oct;52(10):1057-1066. doi: 10.1038/s41588-020-0687-1. Epub 2020 Sep 14. Nat Genet. 2020. PMID: 32929288 Free PMC article.