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HDAC6 modulates myofibril stiffness and diastolic function of the heart.
Lin YH, Major JL, Liebner T, Hourani Z, Travers JG, Wennersten SA, Haefner KR, Cavasin MA, Wilson CE, Jeong MY, Han Y, Gotthardt M, Ferguson SK, Ambardekar AV, Lam MP, Choudhary C, Granzier HL, Woulfe KC, McKinsey TA. Lin YH, et al. Among authors: hourani z. J Clin Invest. 2022 May 16;132(10):e148333. doi: 10.1172/JCI148333. J Clin Invest. 2022. PMID: 35575093 Free PMC article.
Phosphodiesterase 9a Inhibition in Mouse Models of Diastolic Dysfunction.
Methawasin M, Strom J, Borkowski T, Hourani Z, Runyan R, Smith JE 3rd, Granzier H. Methawasin M, et al. Among authors: hourani z. Circ Heart Fail. 2020 May;13(5):e006609. doi: 10.1161/CIRCHEARTFAILURE.119.006609. Epub 2020 May 18. Circ Heart Fail. 2020. PMID: 32418479 Free PMC article.
Triggering typical nemaline myopathy with compound heterozygous nebulin mutations reveals myofilament structural changes as pathomechanism.
Lindqvist J, Ma W, Li F, Hernandez Y, Kolb J, Kiss B, Tonino P, van der Pijl R, Karimi E, Gong H, Strom J, Hourani Z, Smith JE 3rd, Ottenheijm C, Irving T, Granzier H. Lindqvist J, et al. Among authors: hourani z. Nat Commun. 2020 Jun 1;11(1):2699. doi: 10.1038/s41467-020-16526-9. Nat Commun. 2020. PMID: 32483185 Free PMC article.
20 results