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Two-site recognition of Staphylococcus aureus peptidoglycan by lysostaphin SH3b.
Gonzalez-Delgado LS, Walters-Morgan H, Salamaga B, Robertson AJ, Hounslow AM, Jagielska E, Sabała I, Williamson MP, Lovering AL, Mesnage S. Gonzalez-Delgado LS, et al. Among authors: hounslow am. Nat Chem Biol. 2020 Jan;16(1):24-30. doi: 10.1038/s41589-019-0393-4. Epub 2019 Nov 4. Nat Chem Biol. 2020. PMID: 31686030 Free PMC article.
Detection of salt bridges to lysines in solution in barnase.
Williamson MP, Hounslow AM, Ford J, Fowler K, Hebditch M, Hansen PE. Williamson MP, et al. Among authors: hounslow am. Chem Commun (Camb). 2013 Oct 28;49(84):9824-6. doi: 10.1039/c3cc45602a. Chem Commun (Camb). 2013. PMID: 24030197
Molecular basis for bacterial peptidoglycan recognition by LysM domains.
Mesnage S, Dellarole M, Baxter NJ, Rouget JB, Dimitrov JD, Wang N, Fujimoto Y, Hounslow AM, Lacroix-Desmazes S, Fukase K, Foster SJ, Williamson MP. Mesnage S, et al. Among authors: hounslow am. Nat Commun. 2014 Jun 30;5:4269. doi: 10.1038/ncomms5269. Nat Commun. 2014. PMID: 24978025 Free PMC article.
Why the Energy Landscape of Barnase Is Hierarchical.
Pandya MJ, Schiffers S, Hounslow AM, Baxter NJ, Williamson MP. Pandya MJ, et al. Among authors: hounslow am. Front Mol Biosci. 2018 Dec 20;5:115. doi: 10.3389/fmolb.2018.00115. eCollection 2018. Front Mol Biosci. 2018. PMID: 30619881 Free PMC article.
Decoration of the enterococcal polysaccharide antigen EPA is essential for virulence, cell surface charge and interaction with effectors of the innate immune system.
Smith RE, Salamaga B, Szkuta P, Hajdamowicz N, Prajsnar TK, Bulmer GS, Fontaine T, Kołodziejczyk J, Herry JM, Hounslow AM, Williamson MP, Serror P, Mesnage S. Smith RE, et al. Among authors: hounslow am. PLoS Pathog. 2019 May 2;15(5):e1007730. doi: 10.1371/journal.ppat.1007730. eCollection 2019 May. PLoS Pathog. 2019. PMID: 31048927 Free PMC article.
Allomorphy as a mechanism of post-translational control of enzyme activity.
Wood HP, Cruz-Navarrete FA, Baxter NJ, Trevitt CR, Robertson AJ, Dix SR, Hounslow AM, Cliff MJ, Waltho JP. Wood HP, et al. Among authors: hounslow am. Nat Commun. 2020 Nov 2;11(1):5538. doi: 10.1038/s41467-020-19215-9. Nat Commun. 2020. PMID: 33139716 Free PMC article.
An Enzyme with High Catalytic Proficiency Utilizes Distal Site Substrate Binding Energy to Stabilize the Closed State but at the Expense of Substrate Inhibition.
Robertson AJ, Cruz-Navarrete FA, Wood HP, Vekaria N, Hounslow AM, Bisson C, Cliff MJ, Baxter NJ, Waltho JP. Robertson AJ, et al. Among authors: hounslow am. ACS Catal. 2022 Mar 4;12(5):3149-3164. doi: 10.1021/acscatal.1c05524. Epub 2022 Feb 22. ACS Catal. 2022. PMID: 35692864 Free PMC article.
56 results