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Trastuzumab Deruxtecan, Antibody-Drug Conjugate Targeting HER2, Is Effective in Pediatric Malignancies: A Report by the Pediatric Preclinical Testing Consortium.
Hingorani P, Zhang W, Zhang Z, Xu Z, Wang WL, Roth ME, Wang Y, Gill JB, Harrison DJ, Teicher BA, Erickson SW, Gatto G, Kolb EA, Smith MA, Kurmasheva RT, Houghton PJ, Gorlick R. Hingorani P, et al. Among authors: houghton pj. Mol Cancer Ther. 2022 Aug 2;21(8):1318-1325. doi: 10.1158/1535-7163.MCT-21-0758. Mol Cancer Ther. 2022. PMID: 35657346
Testing of new agents in childhood cancer preclinical models: meeting summary.
Houghton PJ, Adamson PC, Blaney S, Fine HA, Gorlick R, Haber M, Helman L, Hirschfeld S, Hollingshead MG, Israel MA, Lock RB, Maris JM, Merlino G, Patterson W, Reynolds CP, Shannon K, Yu A, Yu J, Smith MA. Houghton PJ, et al. Clin Cancer Res. 2002 Dec;8(12):3646-57. Clin Cancer Res. 2002. PMID: 12473573
Biology of childhood osteogenic sarcoma and potential targets for therapeutic development: meeting summary.
Gorlick R, Anderson P, Andrulis I, Arndt C, Beardsley GP, Bernstein M, Bridge J, Cheung NK, Dome JS, Ebb D, Gardner T, Gebhardt M, Grier H, Hansen M, Healey J, Helman L, Hock J, Houghton J, Houghton P, Huvos A, Khanna C, Kieran M, Kleinerman E, Ladanyi M, Lau C, Malkin D, Marina N, Meltzer P, Meyers P, Schofield D, Schwartz C, Smith MA, Toretsky J, Tsokos M, Wexler L, Wigginton J, Withrow S, Schoenfeldt M, Anderson B. Gorlick R, et al. Clin Cancer Res. 2003 Nov 15;9(15):5442-53. Clin Cancer Res. 2003. PMID: 14654523 Review.
IRS-1: auditing the effectiveness of mTOR inhibitors.
Easton JB, Kurmasheva RT, Houghton PJ. Easton JB, et al. Among authors: houghton pj. Cancer Cell. 2006 Mar;9(3):153-5. doi: 10.1016/j.ccr.2006.02.027. Cancer Cell. 2006. PMID: 16530700 Free article. Review.
IGF-I mediated survival pathways in normal and malignant cells.
Kurmasheva RT, Houghton PJ. Kurmasheva RT, et al. Among authors: houghton pj. Biochim Biophys Acta. 2006 Aug;1766(1):1-22. doi: 10.1016/j.bbcan.2006.05.003. Epub 2006 Jun 7. Biochim Biophys Acta. 2006. PMID: 16844299 Review.
Predicted mechanisms of resistance to mTOR inhibitors.
Kurmasheva RT, Huang S, Houghton PJ. Kurmasheva RT, et al. Among authors: houghton pj. Br J Cancer. 2006 Oct 23;95(8):955-60. doi: 10.1038/sj.bjc.6603353. Epub 2006 Sep 5. Br J Cancer. 2006. PMID: 16953237 Free PMC article. Review.
The pediatric preclinical testing program: description of models and early testing results.
Houghton PJ, Morton CL, Tucker C, Payne D, Favours E, Cole C, Gorlick R, Kolb EA, Zhang W, Lock R, Carol H, Tajbakhsh M, Reynolds CP, Maris JM, Courtright J, Keir ST, Friedman HS, Stopford C, Zeidner J, Wu J, Liu T, Billups CA, Khan J, Ansher S, Zhang J, Smith MA. Houghton PJ, et al. Pediatr Blood Cancer. 2007 Dec;49(7):928-40. doi: 10.1002/pbc.21078. Pediatr Blood Cancer. 2007. PMID: 17066459
SK-NEP-1 and Rh1 are Ewing family tumor lines.
Smith MA, Morton CL, Phelps D, Girtman K, Neale G, Houghton PJ. Smith MA, et al. Among authors: houghton pj. Pediatr Blood Cancer. 2008 Mar;50(3):703-6. doi: 10.1002/pbc.21099. Pediatr Blood Cancer. 2008. PMID: 17154184
589 results