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Targeting FANCD2 for therapy sensitization.
Shen C, Houghton PJ. Shen C, et al. Among authors: houghton pj. Oncotarget. 2014 Jun 15;5(11):3426-7. doi: 10.18632/oncotarget.2070. Oncotarget. 2014. PMID: 24913333 Free PMC article. No abstract available.
The mTOR pathway negatively controls ATM by up-regulating miRNAs.
Shen C, Houghton PJ. Shen C, et al. Among authors: houghton pj. Proc Natl Acad Sci U S A. 2013 Jul 16;110(29):11869-74. doi: 10.1073/pnas.1220898110. Epub 2013 Jul 1. Proc Natl Acad Sci U S A. 2013. PMID: 23818585 Free PMC article.
FANCD2 is a potential therapeutic target and biomarker in alveolar rhabdomyosarcoma harboring the PAX3-FOXO1 fusion gene.
Singh M, Leasure JM, Chronowski C, Geier B, Bondra K, Duan W, Hensley LA, Villalona-Calero M, Li N, Vergis AM, Kurmasheva RT, Shen C, Woods G, Sebastian N, Fabian D, Kaplon R, Hammond S, Palanichamy K, Chakravarti A, Houghton PJ. Singh M, et al. Among authors: houghton pj. Clin Cancer Res. 2014 Jul 15;20(14):3884-95. doi: 10.1158/1078-0432.CCR-13-0556. Epub 2014 Apr 30. Clin Cancer Res. 2014. PMID: 24787670 Free PMC article.
The oncogenic role of the cochaperone Sgt1.
Ogi H, Sakuraba Y, Kitagawa R, Xiao L, Shen C, Cynthia MA, Ohta S, Arnold MA, Ramirez N, Houghton PJ, Kitagawa K. Ogi H, et al. Among authors: houghton pj. Oncogenesis. 2015 May 18;4(5):e149. doi: 10.1038/oncsis.2015.12. Oncogenesis. 2015. PMID: 25985210 Free PMC article.
The second European interdisciplinary Ewing sarcoma research summit--A joint effort to deconstructing the multiple layers of a complex disease.
Kovar H, Amatruda J, Brunet E, Burdach S, Cidre-Aranaz F, de Alava E, Dirksen U, van der Ent W, Grohar P, Grünewald TG, Helman L, Houghton P, Iljin K, Korsching E, Ladanyi M, Lawlor E, Lessnick S, Ludwig J, Meltzer P, Metzler M, Mora J, Moriggl R, Nakamura T, Papamarkou T, Radic Sarikas B, Rédini F, Richter GH, Rossig C, Schadler K, Schäfer BW, Scotlandi K, Sheffield NC, Shelat A, Snaar-Jagalska E, Sorensen P, Stegmaier K, Stewart E, Sweet-Cordero A, Szuhai K, Tirado OM, Tirode F, Toretsky J, Tsafou K, Üren A, Zinovyev A, Delattre O. Kovar H, et al. Oncotarget. 2016 Feb 23;7(8):8613-24. doi: 10.18632/oncotarget.6937. Oncotarget. 2016. PMID: 26802024 Free PMC article. Review.
P53 suppresses ribonucleotide reductase via inhibiting mTORC1.
He Z, Hu X, Liu W, Dorrance A, Garzon R, Houghton PJ, Shen C. He Z, et al. Among authors: houghton pj. Oncotarget. 2017 Jun 20;8(25):41422-41431. doi: 10.18632/oncotarget.17440. Oncotarget. 2017. PMID: 28507282 Free PMC article.
589 results