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Nuclear inclusion bodies of mutant and wild-type p53 in cancer: a hallmark of p53 inactivation and proteostasis remodelling by p53 aggregation.
De Smet F, Saiz Rubio M, Hompes D, Naus E, De Baets G, Langenberg T, Hipp MS, Houben B, Claes F, Charbonneau S, Delgado Blanco J, Plaisance S, Ramkissoon S, Ramkissoon L, Simons C, van den Brandt P, Weijenberg M, Van England M, Lambrechts S, Amant F, D'Hoore A, Ligon KL, Sagaert X, Schymkowitz J, Rousseau F. De Smet F, et al. Among authors: houben b. J Pathol. 2017 May;242(1):24-38. doi: 10.1002/path.4872. Epub 2017 Mar 23. J Pathol. 2017. PMID: 28035683
Protein Homeostasis Database: protein quality control in E.coli.
Ramakrishnan R, Houben B, Kreft Ł, Botzki A, Schymkowitz J, Rousseau F. Ramakrishnan R, et al. Among authors: houben b. Bioinformatics. 2020 Feb 1;36(3):948-949. doi: 10.1093/bioinformatics/btz628. Bioinformatics. 2020. PMID: 31392322 Free PMC article.
Exposure of a cryptic Hsp70 binding site determines the cytotoxicity of the ALS-associated SOD1-mutant A4V.
Claes F, Rudyak S, Laird AS, Louros N, Beerten J, Debulpaep M, Michiels E, van der Kant R, Van Durme J, De Baets G, Houben B, Ramakers M, Yuan K, Gwee SSL, Hernandez S, Broersen K, Oliveberg M, Moahamed B, Kirstein J, Robberecht W, Rousseau F, Schymkowitz J. Claes F, et al. Among authors: houben b. Protein Eng Des Sel. 2019 Dec 31;32(10):443-457. doi: 10.1093/protein/gzaa008. Protein Eng Des Sel. 2019. PMID: 32399571
Reverse engineering synthetic antiviral amyloids.
Michiels E, Roose K, Gallardo R, Khodaparast L, Khodaparast L, van der Kant R, Siemons M, Houben B, Ramakers M, Wilkinson H, Guerreiro P, Louros N, Kaptein SJF, Ibañez LI, Smet A, Baatsen P, Liu S, Vorberg I, Bormans G, Neyts J, Saelens X, Rousseau F, Schymkowitz J. Michiels E, et al. Among authors: houben b. Nat Commun. 2020 Jun 5;11(1):2832. doi: 10.1038/s41467-020-16721-8. Nat Commun. 2020. PMID: 32504029 Free PMC article.
Gene Erosion Can Lead to Gain-of-Function Alleles That Contribute to Bacterial Fitness.
Mortier J, Gayán E, Van Eyken R, Torres Montaguth OE, Khodaparast L, Khodaparast L, Houben B, Carpentier S, Rousseau F, Schymkowitz J, Aertsen A. Mortier J, et al. Among authors: houben b. mBio. 2021 Aug 31;12(4):e0112921. doi: 10.1128/mBio.01129-21. Epub 2021 Jul 6. mBio. 2021. PMID: 34225482 Free PMC article.
59 results