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Tumor endothelial cell autophagy is a key vascular-immune checkpoint in melanoma.
EMBO Mol Med. 2023 Dec 7;15(12):e18028. doi: 10.15252/emmm.202318028. Epub 2023 Nov 27.
EMBO Mol Med. 2023.
PMID: 38009521
Free PMC article.
Autophagy in endothelial cells and tumor angiogenesis.
Schaaf MB, Houbaert D, Meçe O, Agostinis P.
Schaaf MB, et al. Among authors: houbaert d.
Cell Death Differ. 2019 Mar;26(4):665-679. doi: 10.1038/s41418-019-0287-8. Epub 2019 Jan 28.
Cell Death Differ. 2019.
PMID: 30692642
Free PMC article.
Review.
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Lysosomal Pathways and Autophagy Distinctively Control Endothelial Cell Behavior to Affect Tumor Vasculature.
Schaaf MB, Houbaert D, Meçe O, To SK, Ganne M, Maes H, Agostinis P.
Schaaf MB, et al. Among authors: houbaert d.
Front Oncol. 2019 Mar 20;9:171. doi: 10.3389/fonc.2019.00171. eCollection 2019.
Front Oncol. 2019.
PMID: 30949450
Free PMC article.
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Lipid droplet degradation by autophagy connects mitochondria metabolism to Prox1-driven expression of lymphatic genes and lymphangiogenesis.
Meçe O, Houbaert D, Sassano ML, Durré T, Maes H, Schaaf M, More S, Ganne M, García-Caballero M, Borri M, Verhoeven J, Agrawal M, Jacobs K, Bergers G, Blacher S, Ghesquière B, Dewerchin M, Swinnen JV, Vinckier S, Soengas MS, Carmeliet P, Noël A, Agostinis P.
Meçe O, et al. Among authors: houbaert d.
Nat Commun. 2022 May 19;13(1):2760. doi: 10.1038/s41467-022-30490-6.
Nat Commun. 2022.
PMID: 35589749
Free PMC article.
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Eating your own fat to stay fit: lipophagy sustains lymphangiogenesis.
Mece O, Houbaert D, Agostinis P.
Mece O, et al. Among authors: houbaert d.
Autophagy. 2023 Apr;19(4):1351-1353. doi: 10.1080/15548627.2022.2117513. Epub 2022 Sep 1.
Autophagy. 2023.
PMID: 36026459
Free PMC article.
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An autophagy program that promotes T cell egress from the lymph node controls responses to immune checkpoint blockade.
Houbaert D, Nikolakopoulos AP, Jacobs KA, Meçe O, Roels J, Shankar G, Agrawal M, More S, Ganne M, Rillaerts K, Boon L, Swoboda M, Nobis M, Mourao L, Bosisio F, Vandamme N, Bergers G, Scheele CLGJ, Agostinis P.
Houbaert D, et al.
Cell Rep. 2024 Apr 23;43(4):114020. doi: 10.1016/j.celrep.2024.114020. Epub 2024 Mar 28.
Cell Rep. 2024.
PMID: 38554280
Free article.
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