Hou Y - Search Results

1

Reducing acetylated tau is neuroprotective in brain injury.

Shin MK, Vázquez-Rosa E, Koh Y, Dhar M, Chaubey K, Cintrón-Pérez CJ, Barker S, Miller E, Franke K, Noterman MF, Seth D, Allen RS, Motz CT, Rao SR, Skelton LA, Pardue MT, Fliesler SJ, Wang C, Tracy TE, Gan L, Liebl DJ, Savarraj JPJ, Torres GL, Ahnstedt H, McCullough LD, Kitagawa RS, Choi HA, Zhang P, Hou Y, Chiang CW, Li L, Ortiz F, Kilgore JA, Williams NS, Whitehair VC, Gefen T, Flanagan ME, Stamler JS, Jain MK, Kraus A, Cheng F, Reynolds JD, Pieper AA. Shin MK, et al. Among authors: hou y. Cell. 2021 May 13;184(10):2715-2732.e23. doi: 10.1016/j.cell.2021.03.032. Epub 2021 Apr 13. Cell. 2021. PMID: 33852912 Free PMC article.

2

A Systems Pharmacology Approach Uncovers Wogonoside as an Angiogenesis Inhibitor of Triple-Negative Breast Cancer by Targeting Hedgehog Signaling.

Huang Y, Fang J, Lu W, Wang Z, Wang Q, Hou Y, Jiang X, Reizes O, Lathia J, Nussinov R, Eng C, Cheng F. Huang Y, et al. Among authors: hou y. Cell Chem Biol. 2019 Aug 15;26(8):1143-1158.e6. doi: 10.1016/j.chembiol.2019.05.004. Epub 2019 Jun 6. Cell Chem Biol. 2019. PMID: 31178408 Free PMC article.

3

Network-based prediction of drug-target interactions using an arbitrary-order proximity embedded deep forest.

Zeng X, Zhu S, Hou Y, Zhang P, Li L, Li J, Huang LF, Lewis SJ, Nussinov R, Cheng F. Zeng X, et al. Among authors: hou y. Bioinformatics. 2020 May 1;36(9):2805-2812. doi: 10.1093/bioinformatics/btaa010. Bioinformatics. 2020. PMID: 31971579 Free PMC article.

4

Network-based drug repurposing for novel coronavirus 2019-nCoV/SARS-CoV-2.

Zhou Y, Hou Y, Shen J, Huang Y, Martin W, Cheng F. Zhou Y, et al. Among authors: hou y. Cell Discov. 2020 Mar 16;6:14. doi: 10.1038/s41421-020-0153-3. eCollection 2020. Cell Discov. 2020. PMID: 32194980 Free PMC article.

5

Phosphorylation of PLCγ1 by EphA2 Receptor Tyrosine Kinase Promotes Tumor Growth in Lung Cancer.

Song W, Kim LC, Han W, Hou Y, Edwards DN, Wang S, Blackwell TS, Cheng F, Brantley-Sieders DM, Chen J. Song W, et al. Among authors: hou y. Mol Cancer Res. 2020 Nov;18(11):1735-1743. doi: 10.1158/1541-7786.MCR-20-0075. Epub 2020 Aug 4. Mol Cancer Res. 2020. PMID: 32753469 Free PMC article.

6

Multimodal single-cell/nucleus RNA sequencing data analysis uncovers molecular networks between disease-associated microglia and astrocytes with implications for drug repurposing in Alzheimer's disease.

Xu J, Zhang P, Huang Y, Zhou Y, Hou Y, Bekris LM, Lathia J, Chiang CW, Li L, Pieper AA, Leverenz JB, Cummings J, Cheng F. Xu J, et al. Among authors: hou y. Genome Res. 2021 Oct;31(10):1900-1912. doi: 10.1101/gr.272484.120. Epub 2021 Feb 24. Genome Res. 2021. PMID: 33627474 Free PMC article.

7

The Epidemiological and Mechanistic Understanding of the Neurological Manifestations of COVID-19: A Comprehensive Meta-Analysis and a Network Medicine Observation.

Shen J, Hou Y, Zhou Y, Mehra R, Jehi L, Cheng F. Shen J, et al. Among authors: hou y. Front Neurosci. 2021 Feb 24;15:606926. doi: 10.3389/fnins.2021.606926. eCollection 2021. Front Neurosci. 2021. PMID: 33732102 Free PMC article.

8

Network medicine links SARS-CoV-2/COVID-19 infection to brain microvascular injury and neuroinflammation in dementia-like cognitive impairment.

Zhou Y, Xu J, Hou Y, Leverenz JB, Kallianpur A, Mehra R, Liu Y, Yu H, Pieper AA, Jehi L, Cheng F. Zhou Y, et al. Among authors: hou y. bioRxiv [Preprint]. 2021 Mar 22:2021.03.15.435423. doi: 10.1101/2021.03.15.435423. bioRxiv. 2021. PMID: 33791705 Free PMC article. Updated. Preprint.

9

Network medicine links SARS-CoV-2/COVID-19 infection to brain microvascular injury and neuroinflammation in dementia-like cognitive impairment.

Zhou Y, Xu J, Hou Y, Leverenz JB, Kallianpur A, Mehra R, Liu Y, Yu H, Pieper AA, Jehi L, Cheng F. Zhou Y, et al. Among authors: hou y. Alzheimers Res Ther. 2021 Jun 9;13(1):110. doi: 10.1186/s13195-021-00850-3. Alzheimers Res Ther. 2021. PMID: 34108016 Free PMC article.

10

Artificial intelligence framework identifies candidate targets for drug repurposing in Alzheimer's disease.

Fang J, Zhang P, Wang Q, Chiang CW, Zhou Y, Hou Y, Xu J, Chen R, Zhang B, Lewis SJ, Leverenz JB, Pieper AA, Li B, Li L, Cummings J, Cheng F. Fang J, et al. Among authors: hou y. Alzheimers Res Ther. 2022 Jan 10;14(1):7. doi: 10.1186/s13195-021-00951-z. Alzheimers Res Ther. 2022. PMID: 35012639 Free PMC article.

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