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Preoperative chemoradiotherapy and postoperative chemotherapy with fluorouracil and oxaliplatin versus fluorouracil alone in locally advanced rectal cancer: initial results of the German CAO/ARO/AIO-04 randomised phase 3 trial.
Rödel C, Liersch T, Becker H, Fietkau R, Hohenberger W, Hothorn T, Graeven U, Arnold D, Lang-Welzenbach M, Raab HR, Sülberg H, Wittekind C, Potapov S, Staib L, Hess C, Weigang-Köhler K, Grabenbauer GG, Hoffmanns H, Lindemann F, Schlenska-Lange A, Folprecht G, Sauer R; German Rectal Cancer Study Group. Rödel C, et al. Among authors: hothorn t. Lancet Oncol. 2012 Jul;13(7):679-87. doi: 10.1016/S1470-2045(12)70187-0. Epub 2012 May 23. Lancet Oncol. 2012. PMID: 22627104 Clinical Trial.
Neoadjuvant rectal score as individual-level surrogate for disease-free survival in rectal cancer in the CAO/ARO/AIO-04 randomized phase III trial.
Fokas E, Fietkau R, Hartmann A, Hohenberger W, Grützmann R, Ghadimi M, Liersch T, Ströbel P, Grabenbauer GG, Graeven U, Hofheinz RD, Köhne CH, Wittekind C, Sauer R, Kaufmann M, Hothorn T, Rödel C; German Rectal Cancer Study Group. Fokas E, et al. Among authors: hothorn t. Ann Oncol. 2018 Jul 1;29(7):1521-1527. doi: 10.1093/annonc/mdy143. Ann Oncol. 2018. PMID: 29718095 Free article. Clinical Trial.
Impact of age on the efficacy of oxaliplatin in the preoperative chemoradiotherapy and adjuvant chemotherapy of rectal cancer: a post hoc analysis of the CAO/ARO/AIO-04 phase III trial.
Hofheinz RD, Arnold D, Fokas E, Kaufmann M, Hothorn T, Folprecht G, Fietkau R, Hohenberger W, Ghadimi M, Liersch T, Grabenbauer GG, Sauer R, Rödel C, Graeven U; German Rectal Cancer Study Group. Hofheinz RD, et al. Among authors: hothorn t. Ann Oncol. 2018 Aug 1;29(8):1793-1799. doi: 10.1093/annonc/mdy205. Ann Oncol. 2018. PMID: 29873684 Free article. Clinical Trial.
Oxaliplatin added to fluorouracil-based preoperative chemoradiotherapy and postoperative chemotherapy of locally advanced rectal cancer (the German CAO/ARO/AIO-04 study): final results of the multicentre, open-label, randomised, phase 3 trial.
Rödel C, Graeven U, Fietkau R, Hohenberger W, Hothorn T, Arnold D, Hofheinz RD, Ghadimi M, Wolff HA, Lang-Welzenbach M, Raab HR, Wittekind C, Ströbel P, Staib L, Wilhelm M, Grabenbauer GG, Hoffmanns H, Lindemann F, Schlenska-Lange A, Folprecht G, Sauer R, Liersch T; German Rectal Cancer Study Group. Rödel C, et al. Among authors: hothorn t. Lancet Oncol. 2015 Aug;16(8):979-89. doi: 10.1016/S1470-2045(15)00159-X. Epub 2015 Jul 15. Lancet Oncol. 2015. PMID: 26189067 Clinical Trial.
Tumor Regression Grading After Preoperative Chemoradiotherapy as a Prognostic Factor and Individual-Level Surrogate for Disease-Free Survival in Rectal Cancer.
Fokas E, Ströbel P, Fietkau R, Ghadimi M, Liersch T, Grabenbauer GG, Hartmann A, Kaufmann M, Sauer R, Graeven U, Hoffmanns H, Raab HR, Hothorn T, Wittekind C, Rödel C; German Rectal Cancer Study Group. Fokas E, et al. Among authors: hothorn t. J Natl Cancer Inst. 2017 Dec 1;109(12). doi: 10.1093/jnci/djx095. J Natl Cancer Inst. 2017. PMID: 29206996 Clinical Trial.
Bagging survival trees.
Hothorn T, Lausen B, Benner A, Radespiel-Tröger M. Hothorn T, et al. Stat Med. 2004 Jan 15;23(1):77-91. doi: 10.1002/sim.1593. Stat Med. 2004. PMID: 14695641
Survival ensembles.
Hothorn T, Bühlmann P, Dudoit S, Molinaro A, van der Laan MJ. Hothorn T, et al. Biostatistics. 2006 Jul;7(3):355-73. doi: 10.1093/biostatistics/kxj011. Epub 2005 Dec 12. Biostatistics. 2006. PMID: 16344280
Flexible modeling of malignant melanoma survival.
Eckel KT, Pfahlberg A, Gefeller O, Hothorn T. Eckel KT, et al. Among authors: hothorn t. Methods Inf Med. 2008;47(1):47-55. doi: 10.3414/me0450. Methods Inf Med. 2008. PMID: 18213427
Generalized maximally selected statistics.
Hothorn T, Zeileis A. Hothorn T, et al. Biometrics. 2008 Dec;64(4):1263-9. doi: 10.1111/j.1541-0420.2008.00995.x. Epub 2008 Mar 5. Biometrics. 2008. PMID: 18325074
111 results