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Vaccine-linked chemotherapy improves cardiac structure and function in a mouse model of chronic Chagas disease.
Jones KM, Mangin EN, Reynolds CL, Villanueva LE, Cruz JV, Versteeg L, Keegan B, Kendricks A, Pollet J, Gusovsky F, Bottazzi ME, Hotez PJ. Jones KM, et al. Among authors: hotez pj. Front Cell Infect Microbiol. 2023 Feb 9;13:1106315. doi: 10.3389/fcimb.2023.1106315. eCollection 2023. Front Cell Infect Microbiol. 2023. PMID: 36844399 Free PMC article.
A Data-Driven Approach to Construct a Molecular Map of Trypanosoma cruzi to Identify Drugs and Vaccine Targets.
Nath SK, Pankajakshan P, Sharma T, Kumari P, Shinde S, Garg N, Mathur K, Arambam N, Harjani D, Raj M, Kwatra G, Venkatesh S, Choudhoury A, Bano S, Tayal P, Sharan M, Arora R, Strych U, Hotez PJ, Bottazzi ME, Rawal K. Nath SK, et al. Among authors: hotez pj. Vaccines (Basel). 2023 Jan 26;11(2):267. doi: 10.3390/vaccines11020267. Vaccines (Basel). 2023. PMID: 36851145 Free PMC article.
A randomized, controlled Phase 1b trial of the Sm-TSP-2 Vaccine for intestinal schistosomiasis in healthy Brazilian adults living in an endemic area.
Diemert DJ, Correa-Oliveira R, Fraga CG, Talles F, Silva MR, Patel SM, Galbiati S, Kennedy JK, Lundeen JS, Gazzinelli MF, Li G, Hoeweler L, Deye GA, Bottazzi ME, Hotez PJ, El Sahly HM, Keitel WA, Bethony J, Atmar RL. Diemert DJ, et al. Among authors: hotez pj. PLoS Negl Trop Dis. 2023 Mar 30;17(3):e0011236. doi: 10.1371/journal.pntd.0011236. eCollection 2023 Mar. PLoS Negl Trop Dis. 2023. PMID: 36996185 Free PMC article. Clinical Trial.
From concept to delivery: a yeast-expressed recombinant protein-based COVID-19 vaccine technology suitable for global access.
Hotez PJ, Adhikari R, Chen WH, Chen YL, Gillespie P, Islam NY, Keegan B, Tyagi Kundu R, Lee J, Liu Z, Kimata JT, Oezguen N, Pollet J, Poveda C, Razavi K, Ronca SE, Strych U, Thimmiraju SR, Versteeg L, Villar-Mondragon MJ, Wei J, Zhan B, Bottazzi ME. Hotez PJ, et al. Expert Rev Vaccines. 2023 Jan-Dec;22(1):495-500. doi: 10.1080/14760584.2023.2217917. Expert Rev Vaccines. 2023. PMID: 37252854 Free article.
Development of chimeric protein as a multivalent vaccine for human Kinetoplastid infections: Chagas disease and leishmaniasis.
Clímaco MC, de Figueiredo LA, Lucas RC, Pinheiro GRG, Dias Magalhães LM, Oliveira ALG, Almeida RM, Barbosa FS, Castanheira Bartholomeu D, Bueno LL, Mendes TA, Zhan B, Jones KM, Hotez P, Bottazzi ME, Oliveira FMS, Fujiwara RT. Clímaco MC, et al. Vaccine. 2023 Aug 23;41(37):5400-5411. doi: 10.1016/j.vaccine.2023.07.020. Epub 2023 Jul 20. Vaccine. 2023. PMID: 37479612
Heterologous mRNA-protein vaccination with Tc24 induces a robust cellular immune response against Trypanosoma cruzi, characterized by an increased level of polyfunctional CD8+ T-cells.
Poveda C, Leão AC, Mancino C, Taraballi F, Chen YL, Adhikari R, Villar MJ, Kundu R, Nguyen DM, Versteeg L, Strych U, Hotez PJ, Bottazzi ME, Pollet J, Jones KM. Poveda C, et al. Among authors: hotez pj. Curr Res Immunol. 2023 Jul 20;4:100066. doi: 10.1016/j.crimmu.2023.100066. eCollection 2023. Curr Res Immunol. 2023. PMID: 37534309 Free PMC article.
604 results