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Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity.
Bartelt A, Widenmaier SB, Schlein C, Johann K, Goncalves RLS, Eguchi K, Fischer AW, Parlakgül G, Snyder NA, Nguyen TB, Bruns OT, Franke D, Bawendi MG, Lynes MD, Leiria LO, Tseng YH, Inouye KE, Arruda AP, Hotamisligil GS. Bartelt A, et al. Among authors: hotamisligil gs. Nat Med. 2018 Mar;24(3):292-303. doi: 10.1038/nm.4481. Epub 2018 Feb 5. Nat Med. 2018. PMID: 29400713 Free PMC article.
A central role for JNK in obesity and insulin resistance.
Hirosumi J, Tuncman G, Chang L, Görgün CZ, Uysal KT, Maeda K, Karin M, Hotamisligil GS. Hirosumi J, et al. Among authors: hotamisligil gs. Nature. 2002 Nov 21;420(6913):333-6. doi: 10.1038/nature01137. Nature. 2002. PMID: 12447443
Obesity-induced inflammatory changes in adipose tissue.
Wellen KE, Hotamisligil GS. Wellen KE, et al. Among authors: hotamisligil gs. J Clin Invest. 2003 Dec;112(12):1785-8. doi: 10.1172/JCI20514. J Clin Invest. 2003. PMID: 14679172 Free PMC article.
Inflammation and metabolic disorders.
Hotamisligil GS. Hotamisligil GS. Nature. 2006 Dec 14;444(7121):860-7. doi: 10.1038/nature05485. Nature. 2006. PMID: 17167474 Review.
Treatment of diabetes and atherosclerosis by inhibiting fatty-acid-binding protein aP2.
Furuhashi M, Tuncman G, Görgün CZ, Makowski L, Atsumi G, Vaillancourt E, Kono K, Babaev VR, Fazio S, Linton MF, Sulsky R, Robl JA, Parker RA, Hotamisligil GS. Furuhashi M, et al. Among authors: hotamisligil gs. Nature. 2007 Jun 21;447(7147):959-65. doi: 10.1038/nature05844. Epub 2007 Jun 6. Nature. 2007. PMID: 17554340 Free PMC article.
209 results