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Page 1
Design, synthesis and biological evaluation of 2-pyrrolone derivatives as radioprotectors.
Satoh H, Ochi S, Mizuno K, Saga Y, Ujita S, Toyoda M, Nishiyama Y, Tada K, Matsushita Y, Deguchi Y, Suzuki K, Tanaka Y, Ueda H, Inaba T, Hosoi Y, Morita A, Aoki S. Satoh H, et al. Among authors: hosoi y. Bioorg Med Chem. 2022 Aug 1;67:116764. doi: 10.1016/j.bmc.2022.116764. Epub 2022 May 9. Bioorg Med Chem. 2022. PMID: 35635928
Evaluation of zinc (II) chelators for inhibiting p53-mediated apoptosis.
Morita A, Ariyasu S, Ohya S, Takahashi I, Wang B, Tanaka K, Uchida T, Okazaki H, Hanaya K, Enomoto A, Nenoi M, Ikekita M, Aoki S, Hosoi Y. Morita A, et al. Among authors: hosoi y. Oncotarget. 2013 Dec;4(12):2439-50. doi: 10.18632/oncotarget.1535. Oncotarget. 2013. PMID: 24280450 Free PMC article.
A Chemical Modulator of p53 Transactivation that Acts as a Radioprotective Agonist.
Morita A, Takahashi I, Sasatani M, Aoki S, Wang B, Ariyasu S, Tanaka K, Yamaguchi T, Sawa A, Nishi Y, Teraoka T, Ujita S, Kawate Y, Yanagawa C, Tanimoto K, Enomoto A, Nenoi M, Kamiya K, Nagata Y, Hosoi Y, Inaba T. Morita A, et al. Among authors: hosoi y. Mol Cancer Ther. 2018 Feb;17(2):432-442. doi: 10.1158/1535-7163.MCT-16-0554. Epub 2017 Sep 22. Mol Cancer Ther. 2018. PMID: 28939557
A Novel RNA Synthesis Inhibitor, STK160830, Has Negligible DNA-Intercalating Activity for Triggering A p53 Response, and Can Inhibit p53-Dependent Apoptosis.
Morita A, Ochi S, Satoh H, Ujita S, Matsushita Y, Tada K, Toyoda M, Nishiyama Y, Mizuno K, Deguchi Y, Suzuki K, Tanaka Y, Ueda H, Inaba T, Hosoi Y, Aoki S. Morita A, et al. Among authors: hosoi y. Life (Basel). 2021 Oct 15;11(10):1087. doi: 10.3390/life11101087. Life (Basel). 2021. PMID: 34685458 Free PMC article.
Potentiality of DNA-dependent protein kinase to phosphorylate Ser46 of human p53.
Komiyama S, Taniguchi S, Matsumoto Y, Tsunoda E, Ohto T, Suzuki Y, Yin HL, Tomita M, Enomoto A, Morita A, Suzuki T, Ohtomo K, Hosoi Y, Suzuki N. Komiyama S, et al. Among authors: hosoi y. Biochem Biophys Res Commun. 2004 Oct 22;323(3):816-22. doi: 10.1016/j.bbrc.2004.08.161. Biochem Biophys Res Commun. 2004. PMID: 15381073
Radiosensitization by hyperthermia in the chicken B-lymphocyte cell line DT40 and its derivatives lacking nonhomologous end joining and/or homologous recombination pathways of DNA double-strand break repair.
Yin HL, Suzuki Y, Matsumoto Y, Tomita M, Furusawa Y, Enomoto A, Morita A, Aoki M, Yatagai F, Suzuki T, Hosoi Y, Ohtomo K, Suzuki N. Yin HL, et al. Among authors: hosoi y. Radiat Res. 2004 Oct;162(4):433-41. doi: 10.1667/rr3239. Radiat Res. 2004. PMID: 15447039
Sodium orthovanadate inhibits p53-mediated apoptosis.
Morita A, Yamamoto S, Wang B, Tanaka K, Suzuki N, Aoki S, Ito A, Nanao T, Ohya S, Yoshino M, Zhu J, Enomoto A, Matsumoto Y, Funatsu O, Hosoi Y, Ikekita M. Morita A, et al. Among authors: hosoi y. Cancer Res. 2010 Jan 1;70(1):257-65. doi: 10.1158/0008-5472.CAN-08-3771. Cancer Res. 2010. PMID: 20048077
352 results